Volumetric reconstruction from confocal slices of a Ramos-RAW cell interface. RTX-Al488-coated (green), PKH26-labelled Ramos cells (red) were incubated with RAW cells for 45 minutes at 37°C. RAW cells were labelled with anti-CD11b-APC (cyan). The RAW cell has extensively trogocytosed both RTX and PKH26. Inset shows the dotted area above it without the PKH26 channel overlaid, revealing the concentration of RTX-Al488 at the cell-cell interface, otherwise depleted from the rest of the Ramos cell. Trogocytosis reaction was halted by fixation 45 min after co-incubation. Ramos cells are approximately 12 μm in diameter.
Trogocytosis (Greek: trogo; gnaw) is when a cell nibbles another cell.[1] It is a process whereby lymphocytes (B, T and NK cells) conjugated to antigen-presenting cells extract surface molecules from these cells and express them on their own surface.[2] The molecular reorganization occurring at the interface between the lymphocyte and the antigen-presenting cell during conjugation is also called "immunological synapse".
^Dance, Amber (2019). "Core Concept: Cells nibble one another via the under-appreciated process of trogocytosis". Proceedings of the National Academy of Sciences. 116 (36): 17608–17610. doi:10.1073/pnas.1912252116. PMC 6731757. PMID 31481628.
^Joly, Etienne; Hudrisier, Denis (September 2003). "What is trogocytosis and what is its purpose?". Nature Immunology. 4 (9): 815. doi:10.1038/ni0903-815. PMID 12942076.
the antigen. Trogocytosis has been initially documented in T, B, and NK cells both in vivo and in vitro. On T cells and B cells, trogocytosis is triggered...
Lymphocystivirus Lymphoproliferative disorders Reactive lymphocyte Secretion assay Trogocytosis All pages with titles containing Lymphocyte All pages with titles containing...
processes in human tissues connected with function of the lymphatic system Trogocytosis Standring S (2016). Gray's anatomy: the anatomical basis of clinical...
-Cytosis is a suffix that either refers to certain aspects of cells ie cellular process or phenomenon or sometimes refers to predominance of certain type...
organism then begins to consume cells of the brain, piecemeal through trogocytosis, by means of an amoebostome, a unique actin-rich sucking apparatus extended...
Hematopoiesis Blood count Haematopoiesis Immune system Innate immune system Trogocytosis White blood cell WebMD (2009). "granulocyte". Webster's New World Medical...
"suckers" or "food cups," which they use for feeding in a manner similar to trogocytosis. The flagellate stage of Naegleria fowleri is pear-shaped and biflagellate...
adhesion molecules. Cell membrane Cell migration Immunological synapse Trogocytosis Cell+Adhesion+Molecules at the U.S. National Library of Medicine Medical...
models Membrane nanotubule History of cell membrane theory Lipid raft Trogocytosis Kimball's Biology pages Archived 2009-01-25 at the Wayback Machine, Cell...
presenting it to B cells. Immune system Immunology Immunological synapse Trogocytosis Janeway Jr CA, Travers P, Walport M, Shlomchik MJ (2001-01-01). "Chapter...
epratuzumab's impact on the body's immune system" via a process called trogocytosis. Other SLE therapies destroy B-cells which compromises the immune system...
are several possibilities how this can be achieved: cell-cell contact (trogocytosis), nanotubes or release of extracellular vesicles such as exosomes. Myeloid...
from the surface of an APC and onto the Treg cell in a process called trogocytosis. Blocking this process with anti-CTLA-4 antibodies is useful for a specific...
low mTEC lifespan II. acquisition of exosomes and III. acquisition via trogocytosis, how antigen transfer can be mediated. There is also an evidence, that...
compartments of the target osteoblasts. A distinct process known as trogocytosis, the exchange of lipid rafts or membrane patches between immune cells...
Mackey-Lawrence; Somlata; Alok Bhattacharya; William A Petri (April 2014). "Trogocytosis by Entamoeba histolytica contributes to cell killing and tissue invasion"...
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