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Transaldolase information


Transaldolase
Identifiers
EC no.2.2.1.2
CAS no.9014-46-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
Transaldolase
Crystallographic structure of human transaldolase.[1][2]
Identifiers
SymbolTransaldolase
PfamPF00923
InterProIPR001585
PROSITEPDOC00741
SCOP21ucw / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1f05​, 1i2n​, 1i2o​, 1i2p​, 1i2q​, 1i2r​, 1l6w​, 1onr​, 1ucw​,1vpx​, 2cwn
transaldolase 1
Identifiers
SymbolTALDO1
NCBI gene6888
HGNC11559
OMIM602063
RefSeqNM_006755
UniProtP37837
Other data
EC number2.2.1.2
LocusChr. 11 p15.5-15.4
Search for
StructuresSwiss-model
DomainsInterPro
transaldolase B
Identifiers
SymboltalB
NCBI gene4199095
PDB1onr
RefSeqNC_008245.1
UniProtP0A870
Other data
EC number2.2.1.2
Search for
StructuresSwiss-model
DomainsInterPro

Transaldolase is an enzyme (EC 2.2.1.2) of the non-oxidative phase of the pentose phosphate pathway. In humans, transaldolase is encoded by the TALDO1 gene.[3][4]

The following chemical reaction is catalyzed by transaldolase:

sedoheptulose 7-phosphate + glyceraldehyde 3-phosphate erythrose 4-phosphate + fructose 6-phosphate
  1. ^ Cite error: The named reference pmid10869557 was invoked but never defined (see the help page).
  2. ^ Molecular graphics images were produced using the UCSF Chimera package from the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco. Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE (October 2004). "UCSF Chimera–a visualization system for exploratory research and analysis". J Comput Chem. 25 (13): 1605–12. CiteSeerX 10.1.1.456.9442. doi:10.1002/jcc.20084. PMID 15264254. S2CID 8747218.
  3. ^ "Entrez Gene: transaldolase 1".
  4. ^ Banki K, Eddy RL, Shows TB, Halladay DL, Bullrich F, Croce CM, Jurecic V, Baldini A, Perl A (October 1997). "The human transaldolase gene (TALDO1) is located on chromosome 11 at p15.4-p15.5". Genomics. 45 (1): 233–8. doi:10.1006/geno.1997.4932. PMID 9339383.

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Transaldolase

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Transaldolase is an enzyme (EC 2.2.1.2) of the non-oxidative phase of the pentose phosphate pathway. In humans, transaldolase is encoded by the TALDO1...

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Transaldolase deficiency

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Transaldolase deficiency is a disease characterised by abnormally low levels of the transaldolase enzyme. It is a metabolic enzyme involved in the pentose...

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Fluorothreonine transaldolase

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In enzymology, a fluorothreonine transaldolase (EC 2.2.1.8) is an enzyme that catalyzes the chemical reaction L-threonine + fluoroacetaldehyde ⇌ {\displaystyle...

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Transaldolase 1

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Transaldolase 1 is a protein that in humans is encoded by the TALDO1 gene. Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway...

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Heptose

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in lipid A biosynthesis. Horecker, B. L; Smyrniotis, P. Z (1953). "Transaldolase: The Formation of Fructose-6-Phosphate from Sedoheptulose-7-Phosphate"...

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Transferase

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EC 2.2. This category consists of various transketolases and transaldolases. Transaldolase, the namesake of aldehyde transferases, is an important part...

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Unibrow

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impaired intellectual development, and polyneuropathy Deficiency of transaldolase DeSanto-Shinawi syndrome due to WAC point mutation Developmental and...

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Tetrose

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transaldolase removes the first 3 carbon molecules of sedoheptulose 7-phosphate and places them onto a glyceraldehyde 3-phosphate. The transaldolase utilizes...

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Pentose phosphate pathway

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glyceraldehyde 3-phosphate → erythrose 4-phosphate + fructose 6-phosphate transaldolase xylulose 5-phosphate + erythrose 4-phosphate → glyceraldehyde 3-phosphate...

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Chromosome 11

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associated factor RNA polymerase 1 subunit D TALDO1 encoding protein Transaldolase 1 TBRG1: transforming growth factor beta regulator 1 TECTA: tectorin...

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Lincomycin

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order of the steps still needs further research. Condensation through a transaldolase (LmbR) of ribose 5-phosphate (C5) with fructose 6-phosphate or...

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Dihydroxyacetone synthase

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Dihydroxyacetone synthase may refer to: Formaldehyde transketolase, an enzyme Transaldolase, an enzyme This disambiguation page lists articles associated with the...

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Sulfoglycolysis

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to the production of the C3 intermediate pyruvate. The sulfofructose transaldolase pathway, first identified in Bacillus aryabhattai and Bacillus megaterium...

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Thiobacillus

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and have been lost. All species are obligate autotrophs (using the transaldolase form of the Calvin-Benson-Bassham cycle) using elementary sulfur, thiosulfate...

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Acidithiobacillus

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the environment. They assimilate carbon from carbon dioxide using the transaldolase variant of the Calvin-Benson-Bassham cycle. The genus comprises motile...

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Sedoheptulose

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1016/S0031-9422(00)91430-4. Horecker, B. L; Smyrniotis, P. Z (1953). "Transaldolase: The Formation of Fructose-6-Phosphate from Sedoheptulose-7-Phosphate"...

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Aldolase A

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siblings with different faces: the mechanisms of FBP and F6P aldolase, transaldolase, transketolase and phosphoketolase revisited in light of recent structural...

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Housekeeping gene

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PGAM5 ENOPH1 Enolase phosphatase LDHA Lactate dehydrogenase TALDO1 Transaldolase in pentose shunt TSTA3 Mannose metabolism SDHA NM_004168 Succinate Dehydrogenase...

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List of enzymes

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transcarbamoylase EC 2.1.3.3 Category:EC 2.2.1 Transketolase EC 2.2.1.1 Transaldolase EC 2.2.1.2 Acetolactate synthase EC 2.2.1.6 2-Succinyl-5-enolpyruvy...

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Bernard Horecker

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pathway. Much of his work, especially of the enzymes on aldolase and transaldolase was done in collaboration with Sandro Pontremoli at the University of...

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Acetolactate synthase

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Code is 2.2.1.6, which means that the enzyme is a transketolase or a transaldolase, which is classified under the transferases that transfer aldehyde or...

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Xylose metabolism

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four genes encoding non-oxidative pentose phosphate pathway enzymes Transaldolase, Transketolase, Ribulose-5-phosphate epimerase and Ribose-5-phosphate...

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