"Toxicology test" redirects here. For drug tests of human subjects, see Drug test.
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U.S. Army Public Health Center Toxicology Lab technician assessing samples
Toxicology testing, also known as safety assessment, or toxicity testing, is the process of determining the degree to which a substance of interest negatively impacts the normal biological functions of an organism, given a certain exposure duration, route of exposure, and substance concentration.[1]
Toxicology testing is often conducted by researchers who follow established toxicology test protocosl for a certain substance, mode of exposure, exposure environment, duration of exposure, a particular organism of interest, or for a particular developmental stage of interest. Toxicology testing is commonly conducted during preclinical development for a substance intended for human exposure. Stages of in silico, in vitro and in vivo research are conducted to determine safe exposure doses in model organisms. If necessary, the next phase of research involves human toxicology testing during a first-in-man study. Toxicology testing may be conducted by the pharmaceutical industry, biotechnology companies, contract research organizations, or environmental scientists.
^Gavanji S, Bakhtari A, Famurewa AC, Othman EM (January 2023). "Cytotoxic Activity of Herbal Medicines as Assessed in Vitro: A Review". Chemistry & Biodiversity. 20 (2): 3–27. doi:10.1002/cbdv.202201098. PMID 36595710. S2CID 255473013.
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Toxicologytesting, also known as safety assessment, or toxicity testing, is the process of determining the degree to which a substance of interest negatively...
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Pharmacology and toxicology. Humana Press. ISBN 978-1-58829-332-9. Bridges BA (November 1980). "The fluctuation test". Archives of Toxicology. 46 (1–2): 41–4...
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