Thalamotomy (Greek: θάλαμος, romanized: thalamus, lit. 'chamber'; Greek: τομή, romanized: tomē, lit. 'cut, slice') is a surgical procedure in which a functional lesion is made into the thalamus to improve the overall brain function in patients. First introduced in the 1950s, it is primarily effective for tremors such as those associated with Parkinson's disease, where a selected portion of the thalamus is surgically destroyed (ablated). Neurosurgeons use specialized equipment to precisely locate an area of the thalamus, usually choosing to work on only one side (the side opposite that of the worst tremors). Bilateral procedures are poorly tolerated because of increased complications and risk, including vision and speech problems. The positive effects on tremors are immediate. Other less destructive procedures are sometimes preferred, such as subthalamic deep brain stimulation, since this procedure can also improve tremors and other symptoms of PD.[1][2][3]
^Fields, Julie A; Tröster, Alexander I (2000). "Cognitive Outcomes after Deep Brain Stimulation for Parkinson's Disease: A Review of Initial Studies and Recommendations for Future Research". Brain and Cognition. 42 (2): 268–293. doi:10.1006/brcg.1999.1104. PMID 10744924. S2CID 2042799.
^Bruce, Beau B; Foote, Kelly D; Rosenbek, John; Sapienza, Christine; Romrell, Janet; Crucian, Greg; Okun, Michael S (2004). "Aphasia and Thalamotomy: Important Issues". Stereotactic and Functional Neurosurgery. 82 (4): 186–190. doi:10.1159/000082207. PMID 15557767. S2CID 34923492.
^Cetas, Justin S; Saedi, Targol; Burchiel, Kim J (2008). "Destructive procedures for the treatment of nonmalignant pain: A structured literature review". Journal of Neurosurgery. 109 (3): 389–404. doi:10.3171/JNS/2008/109/9/0389. PMID 18759567. S2CID 23274820.
surgeries used to treat Parkinson's disease, such as Pallidotomy or Thalamotomy (lesioning procedures), or Deep Brain Stimulation (DBS). During DBS,...
edge detection for quantifying the effectiveness of focused ultrasound thalamotomy for tremor relief". Current Directions in Biomedical Engineering. 9 (1):...
Harrison M, Wintermark M (2013). "A Pilot Study of Focused Ultrasound Thalamotomy for Essential Tremor". New England Journal of Medicine. 369 (7): 640–8...
progression. Thalamotomy is another surgical treatment where lesions of the thalamic nucleus are created to disrupt the tremor circuit. Thalamotomy has been...
It is sometimes regarded as a better alternative to pallidotomy or thalamotomy because it is non-permanent. For optimal installation, the patient is...
TCD can be treated with neurosurgical methods like the central lateral thalamotomy, which due to its invasiveness is only used on patients that have proven...
region of the thalamus Primate basal ganglia system Thalamic stimulator Thalamotomy Harper - index Archived 2015-05-12 at the Wayback Machine & University...
surgery can be both a thalamotomy or the implantation of a thalamic stimulator. Complications are frequent (30% in thalamotomy and 10% in deep brain stimulation)...
special plates and utensils for eating. Surgical intervention such as thalamotomy and deep brain stimulation may ease certain tremors. These surgeries...
successful thalamotomy, it is replaced by hypotonia. Furthermore, significant complications can occur, for example, left ventral-lateral thalamotomy in a right-handed...
involved pallidotomy (i.e., surgical ablation of the globus pallidus) or thalamotomy (i.e., surgical ablation of the thalamus). Instead, a thin lead with...
fail to respond sufficiently to medication, deep brain stimulation and thalamotomy can be highly effective. A "flapping tremor," or asterixis, is characterized...
theatre. He performed a large number of pallidotomies, and later also thalamotomies, in Parkinson's disease and capsulotomies in various forms of mental...
alternative to drug treatment is ventral intermediate nucleus (vim) thalamotomy. The tremors associated with toluene misuse do not seem to be a transient...
treatment options include non-pharmacological therapy. Surgery (pallidotomy, thalamotomy) is often viewed as the last viable option. Around 80% of patients that...
machine learning. TCD can be treated with neurosurgical methods like thalamotomy. Neural oscillations are sensitive to several drugs influencing brain...
Nucleus in Patients with Parkinson Disease with Prior Pallidotomy or Thalamotomy". Brain Sciences. 8 (4): 66. doi:10.3390/brainsci8040066. PMC 5924402...
S2CID 206243361. Kim, M C; B C Son; Y Miyagi; J-K Kang (2002). "Vim thalamotomy for Holmes' tremor secondary to midbrain tumor". Journal of Neurology...
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