Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres.[3][4] TERC serves as a template for telomere replication (reverse transcription) by telomerase. Telomerase RNAs differ greatly in sequence and structure between vertebrates, ciliates and yeasts, but they share a 5' pseudoknot structure close to the template sequence. The vertebrate telomerase RNAs have a 3' H/ACA snoRNA-like domain.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000277925 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Feng J, Funk WD, Wang SS, Weinrich SL, Avilion AA, Chiu CP, et al. (September 1995). "The RNA component of human telomerase". Science. 269 (5228): 1236–41. Bibcode:1995Sci...269.1236F. doi:10.1126/science.7544491. PMID 7544491. S2CID 9440710.
^Jády BE, Richard P, Bertrand E, Kiss T (February 2006). "Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres". Molecular Biology of the Cell. 17 (2): 944–54. doi:10.1091/mbc.E05-09-0904. PMC 1356602. PMID 16319170.
^Lingner J, Hendrick LL, Cech TR (August 1994). "Telomerase RNAs of different ciliates have a common secondary structure and a permuted template". Genes & Development. 8 (16): 1984–98. doi:10.1101/gad.8.16.1984. PMID 7958872.
^Theimer CA, Feigon J (June 2006). "Structure and function of telomerase RNA". Current Opinion in Structural Biology. 16 (3): 307–18. doi:10.1016/j.sbi.2006.05.005. PMID 16713250.
and 21 Related for: Telomerase RNA component information
TelomeraseRNAcomponent, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres...
the telomeraseRNAcomponent (TERC), comprises the most important unit of the telomerase complex. Telomerases are part of a distinct subgroup of RNA-dependent...
each of human telomerase reverse transcriptase (TERT), TelomeraseRNAComponent (TR or TERC), and dyskerin (DKC1). The genes of telomerase subunits, which...
assembly and maturation of human telomeraseRNA. Nonetheless, mutations that directly affect the telomeraseRNAcomponents would presumably exist and should...
58 kilo-daltons. Dyskerin is essential for the activity of telomerase by accumulating telomeraseRNAcomponent (TERC). This gene is a member of the H/ACA snoRNPs...
transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
for the different types of RNA are listed and explained. List of cis-regulatory RNA elements RNA: Types of RNA Non-coding RNA Gribaldo S, Brochier-Armanet...
dysplasia (mutations in FoxF1) Mutations in telomerase reverse transcriptase (TERT) Mutations in telomeraseRNAcomponent (TERC) Mutations in the regulator of...
critical for life. One of the most critical components of cells, the ribosome, is composed primarily of RNA. Ribonucleotide moieties in many coenzymes...
snoRNA to the single hairpin snoRNAs however, unlike trypanosomes, it has a regular ACA motif at 3′ tail.[19] The RNAcomponent of human telomerase (hTERC)...
strand. Telomerase was shown to be a ribonucleoprotein enzyme that contains an RNAcomponent that serves as a template strand, and a protein component that...
Weinrich SL, Avilion AA, Chiu CP, et al. (September 1995). "The RNAcomponent of human telomerase". Science. 269 (5228): 1236–41. Bibcode:1995Sci...269.1236F...
While working at Geron Corporation, Andrews co-discovered the RNAcomponent of human telomerase (hTR). For this discovery, Andrews was awarded second place...
in situ hybridization test, detects amplification of the human telomeraseRNAcomponent (TERC) gene and/or polysomy of chromosome 3. Spectral karyotyping...
biological processes rely on RNA molecules that form pseudoknots. For example, the RNAcomponent of the human telomerase contains a pseudoknot that is...
associated with telomerase assembly and recruitment via a CAB-RNA sequence common in both CB RNAs (scaRNAs) and the RNAcomponent of telomerase (TERC). TCAB1...
TERC may refer to: TelomeraseRNAcomponent, a human gene. TERC (Cambridge, Massachusetts), a nonprofit research and development organization in Cambridge...
(6): 1496–1499. PMID 5158754. Feng F; et al. (1995). "The RNAcomponent of human telomerase". Science. 269 (5228): 1236–1241. Bibcode:1995Sci...269.1236F...
DNA or RNA. Nucleotides consist of 3 components: Nitrogenous base Adenine Guanine Cytosine Thymine (present in DNA only) Uracil (present in RNA only) 5-carbon...
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