Syringocystadenoma papilliferum information

Syringocystadenoma papilliferum
Syringocystadenoma papilliferum
Other names	Syringadenoma papilliferum, Fistulous vegetative verrucous hydradenoma, Naevus syringocystadenomatosus papilliferus, Papillary syringocystadenoma, and SCAP.
	An example of a syringocystadenoma papilliferum
Specialty	Dermatology
Usual onset	Childhood, Neonatal, Infancy, Adolescent.
Causes	Genetic.
Diagnostic method	Skin biopsy.
Differential diagnosis	Hidradenoma papilliferum, Papillary eccrine adenoma, Warty dyskeratoma, Tubular apocrine adenoma, Syringocystadenocarcinoma papilliferum.
Treatment	Surgical excision.

Syringocystadenoma papilliferum is a rare non-malignant adnexal neoplasm that develops from apocrine or eccrine sweat glands and can be identified histologically by cystic, papillary, and ductal invaginations into the dermis lined by double-layered outer cuboidal and luminal high columnar epithelium and connected to the epidermis.^[1]

Lesions have a heterogeneous, non-distinctive appearance that ranges from skin-colored to pink-colored papules or plaques. Typically, lesions form in the head and neck area.^[1]

Syringocystadenoma papilliferum can develop de-novo or within a nevus sebaceous.^[4] Syringocystadenoma papilliferum tends to be seen in children. It is present at birth in approximately 50% of individuals affected, and it develops before puberty in the remaining 15%-30%.^[4]

^ ^a ^b ^c "Syringocystadenoma papilliferum". Orphanet. Retrieved 5 October 2023.
^ "Syringocystadenoma papilliferum — About the Disease — Genetic and Rare Diseases Information Center". rarediseases.info.nih.gov. Retrieved 2023-10-05.
^ ^a ^b ^c "Syringocystadenoma papilliferum". Pathology Outlines. March 10, 2022. Retrieved October 5, 2023.
^ ^a ^b Sangma, Mima Maychet B. (2013). "Syringocystadenoma Papilliferum of the Scalp in an Adult Male – A Case Report". Journal of Clinical and Diagnostic Research. 7 (4): 742–743. doi:10.7860/jcdr/2013/5452.2900. ISSN 2249-782X. PMC 3644463. PMID 23730665.

[orpha-1] "Syringocystadenoma papilliferum". Orphanet. Retrieved 5 October 2023.

[GARD-2] "Syringocystadenoma papilliferum — About the Disease — Genetic and Rare Diseases Information Center". rarediseases.info.nih.gov. Retrieved 2023-10-05.

[Pathology_Outlines-3] "Syringocystadenoma papilliferum". Pathology Outlines. March 10, 2022. Retrieved October 5, 2023.

[Sangma_2013_p.-4] Sangma, Mima Maychet B. (2013). "Syringocystadenoma Papilliferum of the Scalp in an Adult Male – A Case Report". Journal of Clinical and Diagnostic Research. 7 (4): 742–743. doi:10.7860/jcdr/2013/5452.2900. ISSN 2249-782X. PMC 3644463. PMID 23730665.

Syringocystadenoma papilliferum information

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