Ovarian serous cystadenoma. The cystic space is at the top of the image. Ovarian parenchyma is seen at the bottom right. H&E stain.
Specialty
Oncology
Ovarian serous cystadenoma, also (less precisely) known as serous cystadenoma, is the most common ovarian neoplasm, representing 20% of ovarian neoplasms, and is benign.[1]
It has a very superficial resemblance to the most common type of ovarian cancer (serous carcinoma of the ovary) under the microscope; however, (1) it is virtually impossible to mix-up with its malignant counterpart (serous carcinoma), and (2) does not share genetic traits of indeterminate serous tumours, also called serous borderline tumours, that may transform into serous carcinoma.[2]
Serous cystadenomas (of the ovary) are not related to serous cystadenomas of the pancreas, i.e. the presence of an ovarian or pancreatic one does not suggest an increased risk for the other one.
Diagnostic Procedures includes initially ultrasound or colour doppler study to know about size and nature of mass and sometimes CECT. Blood investigation includes CA-125 level for screening and further CEA, beta hCG levels, AFP, CA19-9, LDH level to confirm diagnosis. And before going to surgery routine investigation to be done.
^Peterson CM (1997). "Common Causes of Ovarian Enlargement: Ovarian neoplasms". Human Reproduction. University of Utah Medpath.
^Cheng EJ, Kurman RJ, Wang M, Oldt R, Wang BG, Berman DM, Shih I (June 2004). "Molecular genetic analysis of ovarian serous cystadenomas". Laboratory Investigation; A Journal of Technical Methods and Pathology. 84 (6): 778–784. doi:10.1038/labinvest.3700103. PMID 15077125.
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The condition is extremely rare. The most common version is called cystadenoma. They are usually discovered in the course of examination of the tissue...
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of papillomavirus in this condition. To distinguish between primary ovarianserous carcinoma (OSC) and metastatic squamous cell carcinoma (SCC), various...
representing alternate disease processes such as the more benign serouscystadenoma. Kosary CL (2007). "Chapter 16: Cancers of the Ovary". In Ries LA...
tubal cancer, accessed 08-14-2008 Piek, J. M. J. (2004). Hereditary serousovarian carcinogenesis, a hypothesis (PhD thesis). Vrije Universiteit Amsterdam...
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