Signet ring cell carcinoma metastasis to the ovary, also called Krukenberg tumor: Gross pathology (top, cross-section at right) and histopathology at low and high magnification. The latter shows invasive proliferation of signet-ring cells with a desmoplastic stroma.
Specialty
Oncology
A Krukenberg tumor refers to a malignancy in the ovary that metastasized from a primary site, classically the gastrointestinal tract, although it can arise in other tissues such as the breast.[1] Gastric adenocarcinoma, especially at the pylorus, is the most common source.[2] Krukenberg tumors are often (over 80%)[2] found in both ovaries, consistent with its metastatic nature.[2]
^Ackerman LV, Rosai J (2004). Rosai and Ackerman's surgical pathology. Vol. 2. St. Louis: Mosby. p. 1708. ISBN 0-323-01342-2.
^ abcAl-Agha OM, Nicastri AD (November 2006). "An in-depth look at Krukenberg tumor: an overview". Archives of Pathology & Laboratory Medicine. 130 (11): 1725–1730. doi:10.5858/2006-130-1725-AILAKT. PMID 17076540.
A Krukenbergtumor refers to a malignancy in the ovary that metastasized from a primary site, classically the gastrointestinal tract, although it can arise...
through surgery. A Krukenbergtumor is a quickly developing malignant tumor found in one or both ovaries. In most cases, the tumor primarily originates...
or adenocarcinomata /ˌædɪnoʊkɑːrsɪˈnoʊmətə/; AC) is a type of cancerous tumor that can occur in several parts of the body. It is defined as neoplasia...
surgeon Peter Krukenberg (1787–1865), German pathologist Krukenberg procedure, a surgical technique Krukenbergtumor, a type of cancerous tumor This page...
Neuroendocrine tumors (NETs) are neoplasms that arise from cells of the endocrine (hormonal) and nervous systems. They most commonly occur in the intestine...
A carcinoid (also carcinoid tumor) is a slow-growing type of neuroendocrine tumor originating in the cells of the neuroendocrine system. In some cases...
cancer often metastasises to the ovary in women, when it is called a Krukenbergtumor. According to the "seed and soil" theory, it is difficult for cancer...
PanNETs are a type of neuroendocrine tumor, representing about one-third of gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Many PanNETs are benign...
cytological, or molecular properties of both epithelial tumors ("carcinoma") and mesenchymal tumors ("sarcoma"). It is believed that sarcomatoid carcinomas...
prolactinoma is a tumor (adenoma) of the pituitary gland that produces the hormone prolactin. It is the most common type of functioning pituitary tumor. Symptoms...
A thymoma is a tumor originating from the epithelial cells of the thymus that is considered a rare malignancy. Thymomas are frequently associated with...
A Klatskin tumor (or hilar cholangiocarcinoma) is a cholangiocarcinoma (cancer of the biliary tree) occurring at the confluence of the right and left...
An adenoma is a benign tumor of epithelial tissue with glandular origin, glandular characteristics, or both. Adenomas can grow from many glandular organs...
described a fibrosarcoma of the ovary that was to become known as a Krukenbergtumor. In 1896 he published his findings in an article called Über das Fibrosarcoma...
(plural papillomas or papillomata) (papillo- + -oma) is a benign epithelial tumor growing exophytically (outwardly projecting) in nipple-like and often finger-like...
tumor is often seen in the peritoneum and has also been known to spread to lymphatic permeation of the lungs and to the ovaries, creating Krukenberg tumors...
English: Signet ring cell carcinoma metastasis to the ovary, also called Krukenbergtumor: Gross pathology (top, cross-section at right) and histopathology at...
exploration. The disease is confirmed by examination of cells from the tumor under a microscope. It is typically an adenocarcinoma (a cancer that forms...
to predict for every individual. However, general factors such as high tumor grade, stage, receptor negativity, BRCA1-positivity suggest higher risk...
Sacrococcygeal teratoma (SCT) is a type of tumor known as a teratoma that develops at the base of the coccyx (tailbone) and is thought to be primarily...
A VIPoma or vipoma (/vɪˈpoʊmə/) is a rare endocrine tumor that overproduces vasoactive intestinal peptide (thus VIP + -oma). The incidence is about 1...
local tissue and stromal architecture The anatomical location from which tumors arise Genetic, epigenetic, and molecular features Adenocarcinoma (adeno...
the tumors and adjacent uninvolved mucosa for correct histopathology diagnosis. Low-magnification micrograph of penile verrucous carcinoma. The tumor is...
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