Contractile actin bundles found in non-muscle cells
Stress Fiber
Stress fibers - visualized via fluorescence micrograph of F-actin
Identifiers
MeSH
D022502
TH
H1.00.01.1.02033
Anatomical terminology
[edit on Wikidata]
Stress fibers are contractile actin bundles found in non-muscle cells.[1] They are composed of actin (microfilaments) and non-muscle myosin II (NMMII), and also contain various crosslinking proteins, such as α-actinin, to form a highly regulated actomyosin structure within non-muscle cells.[2] Stress fibers have been shown to play an important role in cellular contractility, providing force for a number of functions such as cell adhesion, migration and morphogenesis.
^Kreis, Thomas E.; Birchmeier, Walter (November 1980). "Stress fiber sarcomeres of fibroblasts are contractile". Cell. 22 (2): 555–561. doi:10.1016/0092-8674(80)90365-7. PMID 6893813. S2CID 11435890.
^Tojkander, S.; Gateva, G.; Lappalainen, P. (April 29, 2012). "Actin stress fibers - assembly, dynamics and biological roles". Journal of Cell Science. 125 (8): 1855–1864. doi:10.1242/jcs.098087. PMID 22544950.
Stressfibers are contractile actin bundles found in non-muscle cells. They are composed of actin (microfilaments) and non-muscle myosin II (NMMII), and...
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bind and hydrolyze GTP, and are important in actin stressfiber formation. Formation of stressfibers may aid in the endocytosis of P. multocida. The host...
is primarily associated with cytoskeleton regulation, mostly actin stressfibers formation and actomyosin contractility. It acts upon several effectors...
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allows actin stressfibers and microtubules to form and align with each other in both colliding partners. The alignment of these stressfibers locally accumulates...
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stressfiber assembly clustering of voltage-gated sodium channels bone development positive regulation of cell migration regulation of stressfiber assembly...
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maintenance of cell viability and morphology, in part by regulating stressfibers and focal adhesions. Particularly, ROCK inhibitor is used for cell culture...
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preventing focal adhesion maturation by inhibiting myosin activity or stressfiber assembly does not prevent forces sustained by focal adhesions, nor does...
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