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Splenocyte information


A splenocyte is a white blood cell that resides in the spleen and are involved in functions of the spleen, like filtering blood and the immune response.[1]

Splenocytes consist of a variety of cell populations such as T and B lymphocytes, dendritic cells and macrophages, which have different immune functions.[2]

  1. ^ "Spleen: Function, Location & Size, Possible Problems". Cleveland Clinic. Retrieved 26 March 2024.
  2. ^ Bronte V, Pittet MJ (November 2013). "The spleen in local and systemic regulation of immunity". Immunity. 39 (5): 806–818. doi:10.1016/j.immuni.2013.10.010. PMC 3912742. PMID 24238338.

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Splenocyte

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A splenocyte is a white blood cell that resides in the spleen and are involved in functions of the spleen, like filtering blood and the immune response...

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Nigella

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Reem; Carr, Ronald I. (15 September 2010). "Nigella sativa modulates splenocyte proliferation, Th1/Th2 cytokine profile, macrophage function and NK anti-tumor...

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effects by inhibiting iNOS and pro-inflammatory cytokine expressions in splenocytes isolated from BALB/c mice". Journal of Functional Foods. 5 (2): 625–632...

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pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes. Sulfate polysaccharides exhibit immunomodulatory, antitumor, antithrombotic...

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Vendrame M, et al. (2006). "Cord blood rescues stroke-induced changes in splenocyte phenotype and function". Exp. Neurol. 199 (1): 191–200. doi:10.1016/j...

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Mast cell

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out using conditioned medium derived from concanavalin A-stimulated splenocytes. Later, it was discovered that T cell-derived interleukin 3 was the component...

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Fat choy

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inflammatory action of white blood cells, specifically macrophages and splenocytes, in vitro. Calvo-Pérez, Juan Diego; Molinari-Novoa, Eduardo A.; Guiry...

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Nostoc commune

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pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes". Biochimica et Biophysica Acta (BBA) - General Subjects. 1830 (4): 2981–2988...

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Celiac ganglia

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Myriam; Oliveros, Liliana; Aguado, Luis (1999). "Effect of Secretion of Splenocytes after Superior Ovarian Nerve Section on the Ovarian Steroidogenesis"...

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MTT assay

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to NAD(P)H flux. Cells with a low metabolism such as thymocytes and splenocytes reduce very little MTT. In contrast, rapidly dividing cells exhibit high...

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HAT medium

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antigen against which we are interested in isolating an antibody. Once splenocytes are isolated from the mammal, the B cells are fused with HGPRT negative...

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Hybridoma technology

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electroporation, which significantly enhances the immune response. Once splenocytes are isolated from the mammal's spleen, the B cells are fused with immortalised...

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Macfarlane Burnet

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did find support for Burnet's hypothesis in 1953 when they showed that splenocytes could be engrafted by intravenous infusion into mice in utero or just...

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Thunberginol A

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thunberginol a and related compounds isolated from hydrangeae dulcis folium on splenocyte proliferation activated by mitogens". Bioorganic & Medicinal Chemistry...

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Lymphocytic choriomeningitis

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destroy infected cells. Their key experiment involved harvesting of splenocytes containing LCMV-specific cytotoxic T lymphocytes(CTL) from an infected...

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Calliandra surinamensis

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Surinamensis Lectin (CasuL) Does Not Impair the Functionality of Mice Splenocytes, Promoting Cell Signaling and Cytokine Production.” Biomedicine & Pharmacotherapy...

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Alloimmunity

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MK, Schwartz RH (1987), Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo...

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CD90

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is only expressed on thymocytes in rats (contrast to thymocytes and splenocytes in mice). The third intron of the mouse Thy-1 gene has a 36 base pair...

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Jungle bush quail

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"Melatonin prevents testosterone-induced suppression of immune parameters and splenocyte proliferation in Indian tropical jungle bush quail, Perdicula asiatica"...

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Xylitol pentanitrate

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dose or concentration (LD, LC): LC50 (median concentration) 148 μM (in splenocytes) Related compounds Related compounds Xylitol Erythritol tetranitrate...

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Tetrabromobisphenol A

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suppress the induction of interleukin-2 receptor α chain (CD25) in murine splenocytes". Toxicology. 184 (1): 11–22. doi:10.1016/S0300-483X(02)00442-0. PMID 12505372...

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Astraeus hygrometricus

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several tumor cell lines in laboratory tests, and stimulated the growth of splenocytes, thymocytes, and bone marrow cells from mice. The extract also stimulated...

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Bacteriophage P2

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Bacteriophages provide regulatory signals in mitogen-induced murine splenocyte proliferation. Cell Mol Biol Lett, 2003. 8(3): p. 699-711. Yu, A. and...

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MRAS

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involved in TNF-alpha-stimulated and Rap1-mediated LFA-1 activation in splenocytes. More generally, cells transfected with M-Ras exhibit dendritic appearances...

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Cynaropicrin

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RAW264.7 cells. Lastly. it also suppressed lymphocyte proliferation from splenocytes. All these compounds, TNF-α, nitric oxide and lymphocytes, are all essential...

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Discodermolide

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non-toxic in vitro. In both human peripheral blood leukocytes and murine splenocytes, (+)-discodermolide was found to suppress the two-way mixed lymphocyte...

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