Transmembrane protein allowing sodium ions in and out
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's membrane.[1][2] They belong to the superfamily of cation channels.
^Jessell TM, Kandel ER, Schwartz JH (2000). Principles of Neural Science (4th ed.). New York: McGraw-Hill. pp. 154–69. ISBN 978-0-8385-7701-1.{{cite book}}: CS1 maint: multiple names: authors list (link)
^Bertil Hillel (2001). Ion Channels of Excitable Membranes (3rd ed.). Sunderland, Mass: Sinauer. pp. 73–7. ISBN 978-0-87893-321-1.
Sodiumchannels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's membrane. They belong to the superfamily...
epithelial sodiumchannel (ENaC), (also known as amiloride-sensitive sodiumchannel) is a membrane-bound ion channel that is selectively permeable to sodium ions...
Sodiumchannel blockers are drugs which impair the conduction of sodium ions (Na+) through sodiumchannels. The following naturally-produced substances...
of the sodiumchannels and are equally large. Cation channels of sperm: This small family of channels, normally referred to as Catsper channels, is related...
A sodiumchannel opener is a type of drug which facilitates ion transmission through sodiumchannels. Examples include toxins, such as aconitine, veratridine...
this is known as depolarization and is mainly due to the opening of sodiumchannels that allow Na+ to flow into the cell. After a delay (known as the absolute...
plasma membrane to reverse, and the ion channels then rapidly inactivate. As the sodiumchannels close, sodium ions can no longer enter the neuron, and...
as either channels or carriers. Examples of channel/carrier proteins include the GLUT 1 uniporter, sodiumchannels, and potassium channels. The solute...
The most commonly involved gene is SCN5A which encodes the cardiac sodiumchannel. Diagnosis is typically by electrocardiogram (ECG), however, the abnormalities...
type of voltage-gated sodiumchannel that underlies action potentials—these are sometimes called Hodgkin-Huxley sodiumchannels because they were initially...
excitatory neurotransmitters via voltage-sensitive sodiumchannels and voltage-gated calcium channels in neurons. Lamotrigine was first marketed in Ireland...
the channel protein. Cloning the channel itself allowed for applications such as identifying the same channels in other animals. Sodiumchannels are known...
potassium channel activity, thereby allowing the study of neuron response contributions of other ion channels such as voltage gated sodiumchannels. In addition...
heart to stop suddenly, known as respiratory arrest and cardiac arrest. Sodiumchannel blockers, like benzocaine, lidocaine, phenytoin, and tricaine methanesulfonate...
opening of voltage-gated sodiumchannels, this results in an influx of sodium ions down their electrochemical gradient. Sodium ions enter the cell, and...
corresponds to the influx of sodium ions, whereas the two decays ("1" and "3", respectively) correspond to the sodium-channel inactivation and the repolarizing...
of the transmembrane sodiumchannel protein. A mutation this gene will cause an individual to develop dysfunctional sodiumchannel Nav 1.1, which is crucial...
Martinez-Lavin M (February 2012). "A SCN9A gene-encoded dorsal root ganglia sodiumchannel polymorphism associated with severe fibromyalgia". BMC Musculoskeletal...
Valproate (valproic acid, VPA, sodium valproate, and valproate semisodium forms) are medications primarily used to treat epilepsy and bipolar disorder...
An epithelial sodiumchannel blocker is a sodiumchannel blocker that is selective for the epithelial sodiumchannel. An example is amiloride, which is...
Sodiumchannel protein type 5 subunit alpha, also known as NaV1.5 is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel...
stabilized by certain channel pores, such as a sodium ion attempting to pass through a potassium channel. In both cases, channel flux is not permitted...
sodiumchannel, NaV1.5, responsible for the sodium current INa which depolarises cardiac cells at the start of the action potential. Cardiac sodium channels...
A variety of alpha subunit voltage-gated sodiumchannels have been identified. Voltage-gated sodiumchannels found in mammals can be divided into three...
Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are a group of medications that disrupt the movement of calcium (Ca2+...
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