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Small nuclear ribonucleoprotein D2 information


SNRPD2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSNRPD2, SMD2, SNRPD1, Sm-D2, Small nuclear ribonucleoprotein D2, small nuclear ribonucleoprotein D2 polypeptide
External IDsOMIM: 601061; MGI: 98345; HomoloGene: 3381; GeneCards: SNRPD2; OMA:SNRPD2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004597
NM_177542
NM_001369751
NM_001369752
NM_001384647

NM_026943

RefSeq (protein)

NP_004588
NP_808210
NP_001356680
NP_001356681

NP_081219

Location (UCSC)Chr 19: 45.69 – 45.69 MbChr 7: 18.88 – 18.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Small nuclear ribonucleoprotein Sm D2 is a protein that in humans is encoded by the SNRPD2 gene.[5][6][7] It belongs to the small nuclear ribonucleoprotein core protein family, and is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125743 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040824 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lehmeier T, Raker V, Hermann H, Luhrmann R (January 1995). "cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction". Proc Natl Acad Sci U S A. 91 (25): 12317–21. Bibcode:1994PNAS...9112317L. doi:10.1073/pnas.91.25.12317. PMC 45428. PMID 7527560.
  6. ^ Lehmeier T, Foulaki K, Luhrmann R (January 1991). "Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5". Nucleic Acids Res. 18 (22): 6475–84. doi:10.1093/nar/18.22.6475. PMC 332598. PMID 1701240.
  7. ^ a b "Entrez Gene: SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa".

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