Serotonergic cell groups refer to collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain the neurotransmitter serotonin (5-hydroxytryptamine).[1] Since they are for the most part localized to classical brainstem nuclei, particularly the raphe nuclei, they are more often referred to by the names of those nuclei than by the B1-9 nomenclature. These cells appear to be common across most mammals and have two main regions in which they develop; one forms in the mesencephlon and the rostral pons and the other in the medulla oblongata and the caudal pons.[2]
Nine serotonergic cell groups have been identified.[3]
^Fuxe K; Hoekfelt T; Ungerstedt U (1970). "Morphological and functional aspects of central monoamine neurons". International Review of Neurobiology. 13: 93–126. doi:10.1016/S0074-7742(08)60167-1. ISBN 9780123668134.
^R. Nieuwenhuys, J. Voogd, C. Van Huijzen, The human central nervous system: a synopsis and atlas (Springer Science & Business Media, 2007).
^Felten DL; Sladek JR Jr. (1983). "Monoamine distribution in primate brain V. Monoaminergic nuclei: anatomy, pathways and local organization". Brain Research Bulletin. 10 (2): 171–284. doi:10.1016/0361-9230(83)90045-x. PMID 6839182. S2CID 13176814.
and 27 Related for: Serotonergic cell groups information
Serotonergiccellgroups refer to collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain...
Film about the history of psychedelic drugs Research chemical Serotonergiccellgroups Serotonin syndrome Tabernanthe iboga TiHKAL Psychedelic drugs Drug...
Thus, it represents the combination of catecholaminergic cellgroups and serotonergiccellgroups. Fuxe K, Hoekfelt T, Ungerstedt U (1970). "Morphological...
Within a nervous system, a neuron, neurone, or nerve cell is an electrically excitable cell that fires electric signals called action potentials across...
of histofluorescence, observed that the majority of serotonergic soma are found in cell body groups, which previously had been designated as the Raphe...
refers to the dense core granules (DCGs), similar to the DCGs in the serotonergic neurons storing monoamines. The term "endocrine" refers to the synthesis...
that the many serotonergic neurons innervate, these pathways are implicated in many functions, as listed above. The caudal serotonergic nuclei heavily...
of histofluorescence, observed that the majority of serotonergic soma are found in cell body groups, which previously had been designated as the raphe...
brain. They receive inputs from dopaminergic, serotonergic, noradrenergic, and cholinergic cellgroups that modulate information processing. Frontostriatal...
Mirtazapine is sometimes described as a noradrenergic and specific serotonergic antidepressant (NaSSA), although the actual evidence in support of this...
genes with important neuronal implications, such as the BDNF gene and serotonergic genes. The brain-derived neurotrophic factor (BDNF) gene plays a role...
wake-promoting cellgroups such as the HA cells of the TM,101 the 5-HT cells of the dorsal Raphe nuclei (DRN),101 the noradrenergic cells of the LC,102...
and in controlling the release of various hormones. These pathways and cellgroups form a dopamine system which is neuromodulatory. In popular culture and...
potential of Gly Cl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway". Disease Models & Mechanisms...
H2-antihistamines. H1-antihistamines work by binding to histamine H1 receptors in mast cells, smooth muscle, and endothelium in the body as well as in the tuberomammillary...
Serotonin modulator and stimulator (SMS) Noradrenergic and specific serotonergic antidepressant (NaSSA) Norepinephrine-dopamine disinhibitor (NDDI) Selective...
striatal, hippocampal, prefrontal, and occipital serotonergic axon terminals. Neurotoxic damage to serotonergic axon terminals has been shown to persist for...
will chemically stimulate neurons. In fact, kainate seems to regulate serotonergic activity in the vertebrate retina. Electrical stimulation of designated...
fiber-specific information; the cerebellum also receives dopaminergic, serotonergic, noradrenergic, and cholinergic inputs that presumably perform global...
the situation. This side effect has been particularly associated with serotonergic antidepressants like SSRIs and SNRIs, but may be less with atypical antidepressants...
another cell across a synapse. The cell receiving the signal, or target cell, may be another neuron, but could also be a gland or muscle cell. Neurotransmitters...
Noradrenergic and specific serotonergic antidepressants antagonize serotonin receptors. Noradrenergic and specific serotonergic antidepressants (NaSSAs)...
Global Information