The secretome is the set of proteins expressed by an organism and secreted into the extracellular space. In humans, this subset of the proteome encompasses 13-20% of all proteins, including cytokines, growth factors, extracellular matrix proteins and regulators, and shed receptors. The secretome of a specific tissue can be measured by mass spectrometry and its analysis constitutes a type of proteomics known as secretomics.
The secretome is the set of proteins expressed by an organism and secreted into the extracellular space. In humans, this subset of the proteome encompasses...
The stem cell secretome (also referred to as the stromal cell secretome) is a collective term for the paracrine soluble factors produced by stem cells...
well as lipids, amino acids, metabolites and small RNAs are found in the secretome of skeletal muscles. Skeletal muscles are substantially composed of multinucleated...
bacterial secretome database. There are also several subcellular location databases with computational predictions, such as the fungal secretome and subcellular...
Secretomics is a type of proteomics which involves the analysis of the secretome—all the secreted proteins of a cell, tissue or organism. Secreted proteins...
only known intracellular pathogen to have a Type II Secretion System (secretome). In Type II Secretion, proteins are first translocated across the inner...
commonly adopt an immunogenic phenotype consisting of a pro-inflammatory secretome, the up-regulation of immune ligands, a pro-survival response, promiscuous...
PMID 14615979. Hathout Y (April 2007). "Approaches to the study of the cell secretome". Expert Review of Proteomics. 4 (2): 239–248. doi:10.1586/14789450.4...
"Aquaphilus dolomiae extract counteracts the effects of cutaneous S. aureus secretome isolated from atopic children on CD4+ T cell activation". Pharmaceutical...
genes are important in the free living and parasitic stages. Excretome/secretome (ES) components essentially consist of proteins and other compounds that...
Simpson; Gert Wörheide; Bernard M Degnan (2006). "A rapidly evolving secretome builds and patterns a sea shell". BMC Biology. 4: 40. doi:10.1186/1741-7007-4-40...
amino acids, metabolites and small RNAs are found in the secretome of skeletal muscles. A secretome is secreted by skeletal muscle cells, either locally (in...
senescent cells and agents that inhibit the pro-inflammatory senescent secretome. Senescent cells can be targeted for immune clearance, but an ageing immune...
enzymes in the ectomycorrhizal fungus Amanita bisporigera, based on the secretome of Trichoderma reesei". Fungal Genetics and Biology. 46 (5): 427–35. doi:10...
across different tissues or conditions. 21. Secretomics: Study of the secretome, the entire set of proteins secreted by a cell, tissue, or organism. 22...
factors and signalling genes are deeply conserved, but the proteins in the secretome are highly derived and rapidly evolving. engrailed serves to demark the...
Reducing the burden of senescent cells, or reducing their inflammatory secretome through CD36 neutralization, accelerates regeneration in young and old...
enzymes in the ectomycorrhizal fungus Amanita bisporigera, based on the secretome of Trichoderma reesei". Fungal Genetics and Biology. 46 (5): 427–435....
2009). "An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion...
behave similarly to extracellular lipid-binding proteins. The Helminth Secretome Database (HSD) is a repository for helminth proteins predicted using expressed...
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