Predicted secondary structure and sequence conservation of CyaR_RyeE
Identifiers
Symbol
CyaR_RyeE
Alt. Symbols
RyeE
Rfam
RF00112
Other data
RNA type
Gene; sRNA
Domain(s)
Bacteria
SO
SO:0000655
PDB structures
PDBe
The CyaR RNA (formerly known as RyeE RNA) non-coding RNA was identified in a large scale screen of Escherichia coli and was called candidate 14.[1] The exact 5′ and 3′ ends of this RNA are uncertain. This gene lies between yegQ and orgK in E. coli. This small RNA was shown to be bound by the Hfq protein. This RNA has been renamed as CyaR for (cyclic AMP-activated
RNA). It has been shown that the CyaR RNA acts as a repressor of the porin OmpX.[2] It has also been shown that cyaR expression is tightly controlled by the cyclic AMP receptor protein, CRP.[2]
A comparative genomics approach was able to detect and verify the additional targets ptsI, sdhA and yobF.[3]
^Wassarman, KM; Repoila F; Rosenow C; Storz G; Gottesman S (2001). "Identification of novel small RNAs using comparative genomics and microarrays". Genes Dev. 15 (13): 1637–1651. doi:10.1101/gad.901001. PMC 312727. PMID 11445539.
^ abPapenfort K, Pfeiffer V, Lucchini S, Sonawane A, Hinton JC, Vogel J (May 2008). "Systematic deletion of Salmonella small RNA genes identifies CyaR, a conserved CRP-dependent riboregulator of OmpX synthesis". Mol. Microbiol. 68 (4): 890–906. doi:10.1111/j.1365-2958.2008.06189.x. PMID 18399940. S2CID 18442940.
^Wright PR, Richter AS, Papenfort K, Mann M, Vogel J, Hess WR, Backofen R, Georg J (2013). "Comparative genomics boosts target prediction for bacterial small RNAs". Proc Natl Acad Sci U S A. 110 (37): E3487–E3496. Bibcode:2013PNAS..110E3487W. doi:10.1073/pnas.1303248110. PMC 3773804. PMID 23980183.
The CyaR RNA (formerly known as RyeERNA) non-coding RNA was identified in a large scale screen of Escherichia coli and was called candidate 14. The exact...
unknown. RyhB RNARyeB RNARyeERNA Wassarman KM, Repoila F, Rosenow C, Storz G, Gottesman S (July 2001). "Identification of novel small RNAs using comparative...
was one of two RNA genes identified in this interval. Other RNAs using this nomenclature include RydB RNA, RyeB RNA, RyeERNA and RyfA RNA. Tjaden B, Goodwin...
of catalytic properties of RNA" 1989 Thomas R. Cech Chicago, Illinois, US "for their discovery of catalytic properties of RNA" 1987 Charles J. Pedersen...
positive-sense single-strand RNA genome approximately 8.5 to 12 kilobases in length, and can be either mono- or bipartite. The RNA serves as both the genome...
of miRNA activity begins with the synthesis of pri-miRNA in the nucleus by RNA polymerase II which is then converted into pre-miRNA. This pre-miRNA exits...
physiological features, and running 16S rRNA sequences to look at each Lactobacillus species separately. An isolate from rye sourdough was discovered to be a...
structure of telomeres, telomerase enzyme, the templating role of telomerase RNA and their roles in cellular senescence and chromosome healing (for which...
Total RNA may be extracted from C. merolae cells using a variant of the hot phenol method described above for DNA. As is the case for DNA and RNA, the...
HMS Seahawk (RNAS Culdrose, Cornwall) RNAS Predannack HMS Heron (RNAS Yeovilton, Somerset) RNAS Merryfield HMS Gannet (formerly known as RNAS Prestwick,...
molecular biology methods, but have so far failed due to a lack of DNA or RNA. Sweating sickness first came to the attention of physicians at the beginning...
Retrieved 3 December 2015. Voloudakis, Andreas E.; Kaldis, Athanasios; Patil, Basavaprabhu L. (29 September 2022). "RNA-Based Vaccination of Plants for Control...
gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling". Journal of Gastroenterology. 50...
second domain is an N-glycosidase that cleaves nucleobases from ribosomal RNA, resulting in inhibition of protein synthesis and cell death. Lectins are...
Tet2 gene knockout RAW264.7 cells; e) itaconate reduced the ability of LPS to stimulate rises in the messenger RNA levels for IL-6 and IL-1β in RAW264...
to copy the DNA into RNA (See: Central dogma of molecular biology). The inaccessible DNA must be unwound to be transcribed into RNA. The mechanism by which...
PMID 12456750. Gill BS, Kimber G (April 1974). "The Giemsa C-banded karyotype of rye". Proceedings of the National Academy of Sciences of the United States of...
Yang Y, Yang E, An Z, Liu X (May 2007). "Evolution of nematode-trapping cells of predatory fungi of the Orbiliaceae based on evidence from rRNA-encoding DNA...
programmed cell death) and inhibit the synthesis of nucleic acids (DNA and RNA) and proteins, reducing the viability of cells. Experiments in vivo with...
Thousands of Missing Coding-Genes and an Unexpected Pool of Grasses Conserved ncRNAs". Tropical Plant Biology. 5 (2): 199–205. doi:10.1007/s12042-012-9103-z....
for Basic Medical Research in 2003 for "pioneering studies on eukaryotic RNA polymerases and the general transcriptional machinery, which opened gene...
Europe. 24: 24. doi:10.1186/2190-4715-24-24. "With BioDirect, Monsanto Hopes RNA Sprays Can Someday Deliver Drought Tolerance and Other Traits to Plants on...
incision lenticule extraction (SMILE) by Walter Sekundo and Marcus Blum 2020: mRNA-based COVID-19 vaccine (BNT162b2) based on research by Uğur Şahin and Özlem...
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