Riligustilide
Names
IUPAC name
(3S ,3′ Z ,5′ aR ,6′ S ,7′ aS )-3′ -Butylidene-6′ -propylspiro[4,5-dihydro-2-benzofuran-3,7′ -5,5a,6,7a-tetrahydro-4H -cyclobuta[g ][2]benzofuran]-1,1′ -dione
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
UNII
6GB38T262B Y
DTXSID101337087
InChI=1S/C24H28O4/c1-3-5-11-19-16-13-12-14-17(8-4-2)24(21(14)20(16)23(26)27-19)18-10-7-6-9-15(18)22(25)28-24/h6,9,11,14,17,21H,3-5,7-8,10,12-13H2,1-2H3/b19-11-/t14-,17+,21+,24-/m1/s1
Key: TYSOMZQRYGBSKN-DRQJQJQISA-N
CCC/C=C\1/C2=C([C@@H]3[C@H](CC2)[C@@H]([C@@]34C5=C(C=CCC5)C(=O)O4)CCC)C(=O)O1
Properties
Chemical formula
C 24 H 28 O 4
Molar mass
380.484 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Riligustilide is a nonsteroidal phytoprogestogen that is found in Ligusticum chuanxiong .[1] [2] It is a very weak agonist of the progesterone receptor (EC50 ≈ 81 μM).[1] Another compound in the plant, 3,8-dihydrodiligustilide, is also a phytoprogestogen, but is almost 1,000-fold more potent in comparison (EC50 = 90 nM).[1]
^ a b c Lim LS, Shen P, Gong YH, Yong EL (2006). "Dimeric progestins from rhizomes of Ligusticum chuanxiong". Phytochemistry . 67 (7): 728–34. doi:10.1016/j.phytochem.2006.01.024. PMID 16516938.
^ Ahmed, H.M.M.; Yeh, J.Y.; Lin, W.J.; Forsberg, N.E.; Cheng, W.T.K.; Ou, B.R (2014). "Validation of a luciferase bioassay to detect the progestative activity in gilts whose estrus was induced by an uterotonic herb (Ligusticum chuanxiong)". Livestock Science . 163 : 159–164. doi:10.1016/j.livsci.2014.02.012. ISSN 1871-1413.
Last Update: 2023-06-29T05:33:32Z
Riligustilide is a nonsteroidal phytoprogestogen that is found in Ligusticum chuanxiong. It is a very weak agonist of the progesterone receptor (EC50...
Word Count : 142
Last Update: 2024-02-18T06:14:56Z
Lovage. It contains the phytoprogestogens 3,8-dihydrodiligustilide and riligustilide . Along with Ligusticum wallichii, L. striatum is one of the possible...
Word Count : 252
Last Update: 2024-05-24T01:32:13Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 18318
Last Update: 2024-05-24T00:52:25Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 8393
Last Update: 2024-05-11T09:25:39Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 11590
Last Update: 2024-06-08T07:18:49Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 1901
Last Update: 2024-05-31T04:01:36Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 7967
Last Update: 2024-05-07T22:31:26Z
mass: 380.1988 u) may refer to: Diethylstilbestrol dipropionate (DESDP) Riligustilide This set index page lists chemical structure articles associated with...
Word Count : 57
Last Update: 2024-03-31T01:51:29Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 2581
Last Update: 2024-05-27T05:00:23Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 6712
Last Update: 2024-04-09T01:29:29Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 4588
Last Update: 2024-03-17T18:41:54Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 1237
Last Update: 2024-06-04T17:48:27Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 11128
Last Update: 2024-06-08T07:23:00Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 3491
Last Update: 2024-04-02T19:45:22Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 123
Last Update: 2023-12-13T09:04:57Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 1566
Last Update: 2024-05-27T16:32:15Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 967
Last Update: 2024-05-13T19:12:59Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 7417
Last Update: 2024-01-06T18:00:09Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 214
Last Update: 2022-10-19T18:09:36Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 478
Last Update: 2024-05-16T08:32:05Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 11654
Last Update: 2024-06-08T21:15:54Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 9319
Last Update: 2024-02-23T20:04:54Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 21601
Last Update: 2023-11-07T19:02:59Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 4847
Last Update: 2024-06-08T18:09:56Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 228
Last Update: 2024-04-05T06:33:34Z
Spirorenone Nonsteroidal: 3,8-Dihydrodiligustilide LG-2527 LG-100128 Riligustilide RWJ-26819 RWJ-49853 RWJ-60130 Tanaproget ZM-182345 Unknown: ORG-47241...
Word Count : 18911