Riboflavin, also known as vitamin B2, is a vitamin found in food and sold as a dietary supplement.[3] It is essential to the formation of two major coenzymes, flavin mononucleotide and flavin adenine dinucleotide. These coenzymes are involved in energy metabolism, cellular respiration, and antibody production, as well as normal growth and development. The coenzymes are also required for the metabolism of niacin, vitamin B6, and folate. Riboflavin is prescribed to treat corneal thinning, and taken orally, may reduce the incidence of migraine headaches in adults.
Riboflavin deficiency is rare and is usually accompanied by deficiencies of other vitamins and nutrients. It may be prevented or treated by oral supplements or by injections. As a water-soluble vitamin, any riboflavin consumed in excess of nutritional requirements is not stored; it is either not absorbed or is absorbed and quickly excreted in urine, causing the urine to have a bright yellow tint. Natural sources of riboflavin include meat, fish and fowl, eggs, dairy products, green vegetables, mushrooms, and almonds. Some countries require its addition to grains.[3]
Riboflavin was discovered in 1920, isolated in 1933, and first synthesized in 1935. In its purified, solid form, it is a water-soluble yellow-orange crystalline powder. In addition to its function as a vitamin, it is used as a food coloring agent. Biosynthesis takes place in bacteria, fungi and plants, but not animals. Industrial synthesis of riboflavin was initially achieved using a chemical process, but current commercial manufacturing relies on fermentation methods using strains of fungi and genetically modified bacteria.
^"Riboflavin". Drugs.com. 22 July 2021. Archived from the original on 30 December 2016. Retrieved 8 October 2021.
^Cite error: The named reference anm was invoked but never defined (see the help page).
^ abc"Riboflavin: Fact Sheet for Health Professionals". Office of Dietary Supplements, US National Institutes of Health. 11 May 2022. Archived from the original on 24 February 2020. Retrieved 20 August 2023.
Riboflavin, also known as vitamin B2, is a vitamin found in food and sold as a dietary supplement. It is essential to the formation of two major coenzymes...
mononucleotide (FMN), or riboflavin-5′-phosphate, is a biomolecule produced from riboflavin (vitamin B2) by the enzyme riboflavin kinase and functions as...
referred to by B-number or by chemical name, such as B1 for thiamine, B2 for riboflavin, and B3 for niacin, while some are more commonly recognized by name than...
phosphoglycerate, riboflavin, dihydroxyacetone, shikimate, and many others. Riboflavin kinase catalyzes the phosphorylation of riboflavin to create flavin...
In enzymology, a riboflavin kinase (EC 2.7.1.26) is an enzyme that catalyzes the chemical reaction ATP + riboflavin ⇌ {\displaystyle \rightleftharpoons...
Riboflavin synthase is an enzyme that catalyzes the final reaction of riboflavin biosynthesis. It catalyzes the transfer of a four-carbon unit from one...
enzymology, a riboflavin phosphotransferase (EC 2.7.1.42) is an enzyme that catalyzes the chemical reaction alpha-D-glucose 1-phosphate + riboflavin ⇌ {\displaystyle...
reduction using riboflavin and UV light is a method by which infectious pathogens in blood for transfusion are inactivated by adding riboflavin and irradiating...
prokaryotic riboflavin biosynthesis protein is a bifunctional enzyme found in bacteria that catalyzes the phosphorylation of riboflavin into flavin mononucleotide...
derivatives thereof. The biochemical source of flavin is the yellow B vitamin riboflavin. The flavin moiety is often attached with an adenosine diphosphate to...
Riboflavin carrier proteins (RFCPs) together with human serum albumin transport flavin mononucleotide (FMN) in the blood circuit. RFCPs are important in...
bonding, catalyze the reduction of these molecules to a reduced flavin. Riboflavin, or vitamin B, and flavin mononucleotide are two of the most well known...
ribulose 5-phosphate, are the precursor compounds for the synthesis of riboflavin (vitamin B2). In the cell, GTP is synthesised through many processes including:...
together would restore activity. Theorell confirmed the pigment to be riboflavin's phosphate ester, flavin mononucleotide (FMN) in 1937, which was the first...
– vitamin A (20%), and vitamin B6 (23% DV), with moderate contents of riboflavin (12%), folate (12% DV), and vitamin E (11% DV). A red bell pepper supplies...
(DV), a serving of yogurt is a rich source of vitamin B12 (31% DV) and riboflavin (23% DV), with moderate content of protein, phosphorus, and selenium (14...
amounts (10–19% DV) of the Daily Value for several dietary minerals, riboflavin, and vitamin B6. Raisins can cause kidney failure in both cats and dogs...
unwanted photochemical process wherein HEPES catalyzes a reaction with riboflavin when exposed to ambient light to produce hydrogen peroxide. This is not...
and makeup: dogs and ferrets use zinc, cats use riboflavin and zinc, and lemurs use only riboflavin.: 17 Choroidal tapetum fibrosum, as seen in cows...
thiamin (B1), riboflavin (B2), niacin (B3), and folic acid (B9). Vitamin B12 is only available through artificial enrichment; riboflavin and folic acid...
produce riboflavin. The most common organism used for production of riboflavin through fermentation is Eremothecium ashbyii. Once riboflavin is produced...
may refer to: Riboflavin, food additive which has been assigned E number 101 Flavin mononucleotide, biomolecule produced from riboflavin European route...