Resistin also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) is a cysteine-rich peptide hormone derived from adipose tissue that in humans is encoded by the RETN gene.[5]
In primates, pigs, and dogs, resistin is secreted by immune and epithelial cells, while, in rodents, it is secreted by adipose tissue. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is an adipose-derived hormone (similar to a cytokine) whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM).[6]
^ abcGRCh38: Ensembl release 89: ENSG00000104918 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000012705 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Wang H, Chu WS, Hemphill C, Elbein SC (June 2002). "Human resistin gene: molecular scanning and evaluation of association with insulin sensitivity and type 2 diabetes in Caucasians". J. Clin. Endocrinol. Metab. 87 (6): 2520–4. doi:10.1210/jcem.87.6.8528. PMID 12050208.
^Lazar MA (October 2007). "Resistin- and Obesity-associated metabolic diseases". Horm. Metab. Res. 39 (10): 710–6. doi:10.1055/s-2007-985897. PMID 17952831.
Resistin also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1)...
serum resistin levels, which in turn directly correlate to insulin resistance. Studies have also confirmed a direct correlation between resistin levels...
major endocrine organ, as it produces hormones such as leptin, estrogen, resistin, and cytokines (especially TNFα). In obesity, adipose tissue is implicated...
Created a Means for Female Empowerment (wordpress.com) Balaji, M. “Vixen Resistin’: Redefining Black Womanhood in Hip-Hop Music Videos.” Journal of Black...
District on Santa Fe, an arts and cultural district in Denver, Colorado, U.S. Resistin, also known as adipose tissue-specific secretory factor Automated Directional...
produce and secrete antimicrobial peptides (AMPs). Production of AMPs resistin and cathelicidin, are promoted by RA. Another way that vitamin A helps...
Chan, DC; Barrett, PH; Watts, GF (2005). "Association of adiponectin and resistin with adipose tissue compartments, insulin resistance and dyslipidaemia"...
ester. White fat cells secrete many proteins acting as adipokines such as resistin, adiponectin, leptin and apelin. An average human adult has 30 billion...
renin); the thymus; skin (cholecalciferol); and adipose tissue (leptin and resistin). Endocrine glands derive from all three germ layers.[citation needed]...
Metastasis-suppressor Diazepam-binding inhibitor Cerebellins Leptin Adiponectin Visfatin Resistin Nucleibindin Ubiquitin Neuromodulators may alter the output of a physiological...
Resistin-like beta is a protein that in humans is encoded by the RETNLB gene. GRCh38: Ensembl release 89: ENSG00000163515 – Ensembl, May 2017 GRCm38: Ensembl...
endocrinologist and physician-scientist known for his discovery of the hormone resistin and his contributions to the transcriptional regulation of metabolism....
produce and secrete antimicrobial peptides (AMPs). Production of AMPs resistin and cathelicidin, are promoted by RA. As some carotenoids can be converted...
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