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RaptorX information


RaptorX
Developer(s)
  • XU Jinbo
  • LI Ming
  • PENG Jian
  • ZHU Jianwei
  • WANG Sheng
Initial release2012; 12 years ago (2012)
Available inEnglish
TypeBioinformatics tool for protein structure prediction
LicenseNonCommercial, case-by-case
Websiteraptorx.uchicago.edu

RaptorX is a software and web server for protein structure and function prediction that is free for non-commercial use. RaptorX is among the most popular methods for protein structure prediction.[1][2][3][4][5] Like other remote homology recognition/protein threading techniques, RaptorX is able to regularly generate reliable protein models when the widely used PSI-BLAST cannot. However, RaptorX is also significantly different from those profile-based methods (e.g., HHPred and Phyre2) in that RaptorX excels at modeling of protein sequences without a large number of sequence homologs by exploiting structure information. RaptorX Server has been designed to ensure a user-friendly interface for users inexpert in protein structure prediction methods.

  1. ^ Peng, Jian; Jinbo Xu (Oct 2011). "RaptorX: exploiting structure information for protein alignment by statistical inference". Proteins. 79 (Suppl 10): 161–71. doi:10.1002/prot.23175. PMC 3226909. PMID 21987485.
  2. ^ Peng, Jian; Jinbo Xu (July 2010). "Low-homology protein threading". Bioinformatics. 26 (12): i294–i300. doi:10.1093/bioinformatics/btq192. PMC 2881377. PMID 20529920.
  3. ^ Peng, Jian; Jinbo Xu (April 2011). "a multiple-template approach to protein threading". Proteins. 79 (6): 1930–1939. doi:10.1002/prot.23016. PMC 3092796. PMID 21465564.
  4. ^ Peng, Jian; Jinbo Xu (January 2009). "Boosting Protein Threading Accuracy". Research in Computational Molecular Biology. Lecture Notes in Computer Science. Vol. 5541. pp. 31–45. doi:10.1007/978-3-642-02008-7_3. ISBN 978-3-642-02007-0. PMC 3325114. PMID 22506254.
  5. ^ Ma, Jianzhu; Sheng Wang; Jinbo Xu (June 2012). "A conditional neural fields model for protein threading". Bioinformatics. 28 (12): i59-66. doi:10.1093/bioinformatics/bts213. PMC 3371845. PMID 22689779.

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