Conversion of an optically active chemical compound into an inactive form
In chemistry, racemization is a conversion, by heat or by chemical reaction, of an optically active compound into a racemic (optically inactive) form. This creates a 1:1 molar ratio of enantiomers and is referred to as a racemic mixture (i.e. contain equal amount of (+) and (−) forms). Plus and minus forms are called Dextrorotation and levorotation.[1] The D and L enantiomers are present in equal quantities, the resulting sample is described as a racemic mixture or a racemate. Racemization can proceed through a number of different mechanisms, and it has particular significance in pharmacology as different enantiomers may have different pharmaceutical effects.
^Kennepohl D, Farmer S (2019-02-13). "6.7: Optical Activity and Racemic Mixtures". Chemistry LibreTexts. Retrieved 2022-11-16.
In chemistry, racemization is a conversion, by heat or by chemical reaction, of an optically active compound into a racemic (optically inactive) form...
A raceme (/reɪˈsiːm, rə-/) or racemoid is an unbranched, indeterminate type of inflorescence bearing flowers having short floral stalks along the shoots...
racemization. Thus, measuring the ratio of D to L in a sample enables one to estimate how long ago the specimen died. The rate at which racemization proceeds...
undergo "umbrella inversion" at room temperature, leading to racemization. If the racemization is fast enough, the molecule can often be treated as an achiral...
Racemic acid is an old name for an optically inactive or racemic form of tartaric acid. It is an equal mixture of two mirror-image isomers (enantiomers)...
Nepeta racemosa, the dwarf catnip or raceme catnip, syn. N. mussiniii, is a species of flowering plant in the mint family Lamiaceae, native to the Caucasus...
(v.3 - Jan 2020), retrieved 2020-07-31 J L Bada (1985). "Amino Acid Racemization Dating of Fossil Bones". Annual Review of Earth and Planetary Sciences...
Racemic crystallography is a technique used in structural biology where crystals of a protein molecule are developed from an equimolar mixture of an L-protein...
(pKa 4.60) and suppresses base catalyzed side reactions, in particular racemization. Ethyl cyanohydroxyiminoacetate is obtained in the reaction of ethyl...
a value near 0 towards an equilibrium value near 1, a process called racemization. Thus, measuring the ratio of D to L in a sample enables one to estimate...
energy than the transition states for hydrogenation, resulting in rapid racemization and high yields of a single enantiomer of the product. The enantiomers...
Akebia longeracemosa or long-racemed akebia is a member of the chocolate vine genus, Akebia, and more specifically a relative of the commonly known, Akebia...
Chiral drugs that are equimolar (1:1) mixture of enantiomers are called racemic drugs and these are obviously devoid of optical rotation. The most commonly...
It is the "left-handed" (levorotatory) stereoisomer of racemorphan, the racemic mixture of the two stereoisomers with differing pharmacology. The "right-handed"...
Methamphetamine properly refers to a specific chemical substance, the racemic free base, which is an equal mixture of levomethamphetamine and dextromethamphetamine...
crystal). Anhydrous HOBt is explosive. It is mainly used to suppress the racemization of single-enantiomer chiral molecules and to improve the efficiency of...
peptide synthesis. It was introduced in 1978 and shows resistance against racemization. It is used because of its mild activating properties. The product obtained...
dextroamphetamine. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers in their pure amine...
chirality of the acetate center at a rate fast enough to ensure complete racemization. When this is achieved the CALB enzyme selectively hydrolyzes the (R)...
activation opens the possibility for racemization of the activated amino acid. Racemization can be circumvented with 'racemization suppressing' additives such...
thyrsiflorum is a species of orchid, commonly called the pinecone-like raceme dendrobium. It is native to the Himalayas (Bhutan, Assam, Yunnan and Arunachal...
Dendrobium lituiflorum, the bent-racemed dendrobium, is a species of orchid. It is native to southern China (Yunnan, Guangxi), the Himalayas (Arunachal...
heart contractility and cardiac output. Dobutamine is administered as a racemic mixture consisting of both (+) and (−) isomers; the (+) isomer is a potent...
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