Hydroxybenzotriazole information

Hydroxybenzotriazole
Names
	Preferred IUPAC name 1H-1,2,3-Benzotriazol-1-ol
	Other names N-Hydroxybenzotriazole; HOBt
Identifiers
CAS Number	2592-95-2 ; (monohydrate): 80029-43-2 ;
3D model (JSmol)	Interactive image;
ChemSpider	68282 ;
ECHA InfoCard	100.018.173
EC Number	219-989-7; (monohydrate): 602-929-2;
PubChem CID	75771; (monohydrate): 2796029;
UNII	A2T929DMG4 ; (monohydrate): S72K7GY45F ;
CompTox Dashboard (EPA)	DTXSID3044627 ;
	InChI InChI=1S/C6H5N3O/c10-9-6-4-2-1-3-5(6)7-8-9/h1-4,10H Key: ASOKPJOREAFHNY-UHFFFAOYSA-N ; InChI=1/C6H5N3O/c10-9-6-4-2-1-3-5(6)7-8-9/h1-4,10H Key: ASOKPJOREAFHNY-UHFFFAOYAP;
	SMILES n1nn(O)c2ccccc12;
Properties
Chemical formula	C6H5N3O
Molar mass	135.1234 g mol−1 (anhydrous)
Melting point	156 to 159 °C (313 to 318 °F; 429 to 432 K) (decomposes)
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H203
Precautionary statements	P210, P230, P240, P250, P280, P370+P380, P372, P373, P401, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Hydroxybenzotriazole (abbreviated HOBt) is an organic compound that is a derivative of benzotriazole. It is a white crystalline powder, which as a commercial product contains some water (~11.7% wt as the HOBt monohydrate crystal). Anhydrous HOBt is explosive.

It is mainly used to suppress the racemization of single-enantiomer chiral molecules and to improve the efficiency of peptide synthesis.

Hydroxybenzotriazole information

and 11 Related for: Hydroxybenzotriazole information

Hydroxybenzotriazole

Steglich esterification

Tolyltriazole

HBTU

Dichloromethane

Carbodiimide

Active ester

List of UN numbers 3401 to 3500

List of UN numbers 0501 to 0600

Ethyl cyanohydroxyiminoacetate

Weinreb ketone synthesis

Names


Preferred IUPAC name 1H-1,2,3-Benzotriazol-1-ol
Other names N-Hydroxybenzotriazole HOBt
Identifiers
CAS Number	2592-95-2^Y (monohydrate): 80029-43-2^Y
3D model (JSmol)	Interactive image
ChemSpider	68282^Y
ECHA InfoCard	100.018.173
EC Number	219-989-7 (monohydrate): 602-929-2
PubChem CID	75771 (monohydrate): 2796029
UNII	A2T929DMG4^Y (monohydrate): S72K7GY45F^Y
CompTox Dashboard (EPA)	DTXSID3044627
InChI InChI=1S/C6H5N3O/c10-9-6-4-2-1-3-5(6)7-8-9/h1-4,10H^Y Key: ASOKPJOREAFHNY-UHFFFAOYSA-N^N InChI=1/C6H5N3O/c10-9-6-4-2-1-3-5(6)7-8-9/h1-4,10H Key: ASOKPJOREAFHNY-UHFFFAOYAP
SMILES n1nn(O)c2ccccc12
Properties
Chemical formula	C₆H₅N₃O
Molar mass	135.1234 g mol⁻¹ (anhydrous)
Melting point	156 to 159 °C (313 to 318 °F; 429 to 432 K) (decomposes)
Hazards
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H203
Precautionary statements	P210, P230, P240, P250, P280, P370+P380, P372, P373, P401, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references