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ROCK2 information


ROCK2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesROCK2, ROCK-II, Rho associated coiled-coil containing protein kinase 2
External IDsOMIM: 604002; MGI: 107926; HomoloGene: 21010; GeneCards: ROCK2; OMA:ROCK2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004850
NM_001321643

NM_009072

RefSeq (protein)

NP_001308572
NP_004841

NP_033098

Location (UCSC)Chr 2: 11.18 – 11.35 MbChr 12: 16.89 – 16.99 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. [5]Fasudil is an inhibitor of ROCK protein.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000134318 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020580 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Rho associated coiled-coil containing protein kinase 2". Retrieved 2016-04-21.

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ROCK2

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containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. Fasudil is an inhibitor of ROCK protein. The protein encoded by this...

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Belumosudil

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coiled-coil kinase 2 (ROCK2; ROCK-II). Belumosudil binds to and inhibits the serine/threonine kinase activity of ROCK2. This inhibits ROCK2-mediated signaling...

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Dean Ween

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Records. Melchiondo's second solo album under The Dean Ween Group moniker, rock2, was released on March 16, 2018. with Ween GodWeenSatan: The Oneness (1990)...

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Rho family of GTPases

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Rock1, Rock2, PrkcA, Ppp1r12A Rac1 Sra1, IRSp53, PAK1, PAK2, PAK3 Cdc42 Wiskott-Aldrich syndrome protein, N-WASP, IRSp53, Dia2, Dia3, ROCK1, ROCK2, PAK4...

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Quratulain Balouch

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Pakistan YouTube (25 March 2017). "Chal Diye by QB and Ali Azmat #CornettoPopRock2". Retrieved 24 September 2017 – via YouTube. "LSA 2018 entertainment nominations...

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Three on a Rope

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Tahquitz-rock2...

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Charisma Records

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SWE #10, US #28 CAN: Platinum, UK, US: Gold 1983 Malcolm McLaren Duck Rock2 UK #18 UK: Silver 1983 Steve Hackett Highly Strung UK #16 1983 Peter Gabriel...

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Rho kinase inhibitor

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multi-specific ATP competitive inhibitor of activity of ROCK1 (IC50 of 5 nM), ROCK2 (IC50 of 50 nM), MRCKα (IC50 of 10 nM) and MRCKβ (IC50 of 100 nM) kinases...

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Kadmon Corporation

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These compounds include SLx-2119 (KD025), an inhibitor to Rho kinase 2 (ROCK2) with possible potential in fibrotic disease and focal cerebral ischemia...

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City of Ipswich

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Mutdapilly1 Peak Crossing1 Pine Mountain Purga Rosewood South Ripley Spring Mountain Tallegalla Thagoona The Bluff Walloon White Rock2 Willowbank Woolshed...

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Justin Stebbing

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for fibrosis, inflammation and metabolism based on selective targeting of ROCK2. "Professor Justin Stebbing - ARU". aru.ac.uk. ARU. Retrieved 2022-11-30...

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Pleckstrin homology domain

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RALGPS2, RAPH1, RASA1, RASA2, RASA3, RASA4, RASAL1, RASGRF1, RGNEF, ROCK1, ROCK2, RTKN, SBF1, SBF2, SCAP2, SGEF, SH2B, SH2B1, SH2B2, SH2B3, SH3BP2, SKAP1...

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Momina Mustehsan

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YouTube (10 September 2017). "Jee Liya By Momina Mustehsan #CornettoPopRock2". Retrieved 11 September 2017 – via YouTube. Times Music (17 January 2019)...

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C1 domain

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RAF1; RASGRP; RASGRP1; RASGRP2; RASGRP3; RASGRP4; RASSF1; RASSF5; ROCK1; ROCK2; STAC; STAC2; STAC3; TENC1; UNC13A; UNC13B; UNC13C; VAV1; VAV2; VAV3; Azzi...

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Rock2Wgtn

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Wellington... not easter... new artists!", along with a new logo that says "Rock2????". However mid-2009 it got changed to Rock22010 with no word on delays...

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Adam Lasus

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Producer/Engineer 2019 Son Of Stan Diamond Cuts Wizardvision Engineer 2018 Dean Ween Rock2 Schnitzel Records Engineer 2017 Happyness Write In Bar/None Records Mixer/Engineer...

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City of Cairns

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Little Mulgrave Meringa Miriwinni Mount Peter Mount Sheridan Ngatjan1 Packers Camp Waugh Pocket White Rock2 Woopen Creek Wooroonooran3 Woree Wrights Creek...

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Protein kinase domain

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RIOK1 ; RIOK2 ; RIOK3 ; RIPK1 ; RIPK2 ; RIPK3 ; RIPK4 ; RNASEL ; ROCK1 ; ROCK2 ; ROR1 ; ROR2 ; ROS1 ; RPS6KA1 ; RPS6KA2 ; RPS6KA3 ; RPS6KA4 ; RPS6KA5 ;...

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ROCK1

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subcellular localization. There is one other isoform of ROCK known as ROCK2. ROCK2 is located at 2p24 and is highly homologous with ROCK1 with an overall...

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SLC66A3

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contains 7 exons. The SLC66A3 gene is neighbored by the genes ROCK2, C2orf50, and KCNF1. ROCK2 and C2orf50 are both located upstream of SLC66A3 whereas KCNF1...

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