SLC66A3, C2orf22, PQ loop repeat containing 3, solute carrier family 66 member 3, PQLC3
External IDs
MGI: 2444067 HomoloGene: 16454 GeneCards: SLC66A3
Gene location (Human)
Chr.
Chromosome 2 (human)[1]
Band
2p25.1
Start
11,155,198 bp[1]
End
11,178,870 bp[1]
Gene location (Mouse)
Chr.
Chromosome 12 (mouse)[2]
Band
12|12 A1.1
Start
17,038,649 bp[2]
End
17,050,409 bp[2]
RNA expression pattern
Bgee
Human
Mouse (ortholog)
Top expressed in
oocyte
secondary oocyte
monocyte
synovial membrane
germinal epithelium
Achilles tendon
corpus epididymis
gallbladder
tibial nerve
right coronary artery
Top expressed in
olfactory epithelium
corneal stroma
mucous cell of stomach
carotid body
right lung lobe
epithelium of stomach
white adipose tissue
yolk sac
blood
spleen
More reference expression data
BioGPS
n/a
Orthologs
Species
Human
Mouse
Entrez
130814
217430
Ensembl
ENSG00000162976
ENSMUSG00000045679
UniProt
Q8N755
Q8C6U2
RefSeq (mRNA)
NM_001282710 NM_001282711 NM_001282712 NM_152391
NM_001161111 NM_172574
RefSeq (protein)
NP_001269639 NP_001269640 NP_001269641 NP_689604
NP_766162
Location (UCSC)
Chr 2: 11.16 – 11.18 Mb
Chr 12: 17.04 – 17.05 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Solute carrier family 66 member 3 is a gene in humans that encodes the protein SLC66A3. The function of the SLC66A3 protein is not yet well understood but belongs to a family of five evolutionarily related proteins, the SLC66 lysosomal amino acid transporters.[5] SLC66A3 is localized to the endoplasmic reticulum and has four transmembrane domains.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000162976 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000045679 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Gyimesi G, Hediger MA (2021-06-25). "SLC66 Lysosomal amino acid transporters in GtoPdb v.2021.2". IUPHAR/BPS Guide to Pharmacology CITE. 2021 (2). doi:10.2218/gtopdb/F1048/2021.2. ISSN 2633-1020. S2CID 237877056.
^Cite error: The named reference :2 was invoked but never defined (see the help page).
66 member 3 is a gene in humans that encodes the protein SLC66A3. The function of the SLC66A3 protein is not yet well understood but belongs to a family...
Global Information
