RANBP3 information

RANBP3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CRF, 2Y8F, 2Y8G
Identifiers
Aliases	RANBP3, RAN binding protein 3
External IDs	OMIM: 603327; MGI: 1919060; HomoloGene: 136516; GeneCards: RANBP3; OMA:RANBP3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	5,978,142 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	57,018,764 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; ventricular zone; ; ganglionic eminence; ; stromal cell of endometrium; ; gallbladder; ; left testis; ; muscle layer of sigmoid colon; ; gastric mucosa; ; popliteal artery; ; tibial arteries;
	Top expressed in
	spermatocyte; ; ventricular zone; ; epiblast; ; Ileal epithelium; ; yolk sac; ; neural layer of retina; ; primitive streak; ; spermatid; ; secondary oocyte; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	R-SMAD binding; protein binding; GTPase activator activity;
Cellular component	nucleoplasm; nucleus; cytoplasm; centrosome; nuclear pore;
Biological process	protein transport; intracellular transport; RNA export from nucleus; ubiquitin-dependent protein catabolic process; protein import into nucleus; spindle organization; positive regulation of GTPase activity; positive regulation of mitotic centrosome separation; G1/S transition of mitotic cell cycle; protein export from nucleus;
	Sources:Amigo / QuickGO
Orthologs
	8498
	71810
	ENSG00000031823
	ENSMUSG00000002372
	Q9H6Z4
	Q9CT10
	NM_001300865; NM_003624; NM_007320; NM_007321; NM_007322
	NM_001252466; NM_001252467; NM_027933
	NP_001287794; NP_003615; NP_015559; NP_015561
	NP_001239395; NP_001239396; NP_082209
	Wikidata
View/Edit Human	View/Edit Mouse

Ran-binding protein 3 is a protein that in humans is encoded by the RANBP3 gene.^[5]^[6]

This gene encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000031823 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000002372 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mueller L, Cordes VC, Bischoff FR, Ponstingl H (July 1998). "Human RanBP3, a group of nuclear RanGTP binding proteins". FEBS Lett. 427 (3): 330–6. doi:10.1016/S0014-5793(98)00459-1. PMID 9637251. S2CID 28405923.
^ ^a ^b "Entrez Gene: RANBP3 RAN binding protein 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000031823 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000002372 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9637251-5] Mueller L, Cordes VC, Bischoff FR, Ponstingl H (July 1998). "Human RanBP3, a group of nuclear RanGTP binding proteins". FEBS Lett. 427 (3): 330–6. doi:10.1016/S0014-5793(98)00459-1. PMID 9637251. S2CID 28405923.

[entrez-6] "Entrez Gene: RANBP3 RAN binding protein 3".

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