Global InformationQuantitative insulin sensitivity check index information
The quantitative insulin sensitivity check index (QUICKI) is derived using the inverse of the sum of the logarithms of the fasting insulin and fasting glucose:
- 1 / (log(fasting insulin μU/mL) + log(fasting glucose mg/dL))
This index correlates well with glucose clamp studies (r = 0.78), and is useful for measuring insulin sensitivity (IS), which is the inverse of insulin resistance (IR). It has the advantage of that it can be obtained from a fasting blood sample, and is the preferred method for certain types of clinical research.
There are no documented reference value for QUICKI.[1] In one study, 95% of healthy persons had a QUICKI index above 0.357.[2] Another study concluded that QUICKI index 0.3469 or below should be used to determine insulin resistance.[3]
- ^ Tohidi, Maryam; Ghasemi, Asghar; Hadaegh, Farzad; Derakhshan, Arash; Chary, Abdolreza; Azizi, Fereidoun (2014). "Age- and sex-specific reference values for fasting serum insulin levels and insulin resistance/sensitivity indices in healthy Iranian adults: Tehran Lipid and Glucose Study". Clinical Biochemistry. 47 (6): 432–438. doi:10.1016/j.clinbiochem.2014.02.007. PMID 24530467.
- ^ Hřebíček, Jiří; Janout, Vladimír; Malinčíková, Jana; Horáková, Dagmar; Čížek, Luděk (2002-01-01). "Detection of Insulin Resistance by Simple Quantitative Insulin Sensitivity Check Index QUICKI for Epidemiological Assessment and Prevention". The Journal of Clinical Endocrinology & Metabolism. 87 (1): 144–147. doi:10.1210/jcem.87.1.8292. ISSN 0021-972X. PMID 11788638.
- ^ Gokcel, A.; Baltali, M.; Tarim, E.; Bagis, T.; Gumurdulu, Y.; Karakose, H.; Yalcin, F.; Akbaba, M.; Guvener, N. (2003). "Detection of insulin resistance in Turkish adults: a hospital-based study: Detection of insulin resistance in Turkish adults". Diabetes, Obesity and Metabolism. 5 (2): 126–130. doi:10.1046/j.1463-1326.2003.00253.x. PMID 12630938. S2CID 46611787.