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Pyruvate synthase information


pyruvate synthase
pyruvate synthase dimer, Desulfovibrio africanus
Identifiers
EC no.1.2.7.1
CAS no.9082-51-3
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MetaCycmetabolic pathway
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In enzymology, a pyruvate synthase (EC 1.2.7.1) is an enzyme that catalyzes the interconversion of pyruvate and acetyl-CoA. It is also called pyruvate:ferredoxin oxidoreductase (PFOR).

The relevant equilibrium catalysed by PFOR is:

pyruvate + CoA + oxidized ferredoxin acetyl-CoA + CO2 + reduced ferredoxin

The 3 substrates of this enzyme are pyruvate, CoA, and oxidized ferredoxin, whereas its 3 products are acetyl-CoA, CO2, and reduced ferredoxin.

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Pyruvate synthase

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enzymology, a pyruvate synthase (EC 1.2.7.1) is an enzyme that catalyzes the interconversion of pyruvate and acetyl-CoA. It is also called pyruvate:ferredoxin...

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Acetolactate synthase

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bacteria. Acetolactate synthase, also known as acetohydroxy acid synthase, is an enzyme specifically involved in the conversion of pyruvate to acetolactate:...

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Cellular respiration

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carbon chains which later degrades into pyruvate.: 88–90  Pyruvate is oxidized to acetyl-CoA and CO2 by the pyruvate dehydrogenase complex (PDC). The PDC...

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Pyruvate carboxylase

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Pyruvate carboxylase (PC) encoded by the gene PC is an enzyme (EC 6.4.1.1) of the ligase class that catalyzes (depending on the species) the physiologically...

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Indolepyruvate ferredoxin oxidoreductase

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3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase (decarboxylating, CoA-indole-acetylating). Other names in common use include 3-(indol-3-yl)pyruvate synthase (ferredoxin)...

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Shikimate pathway

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with phosphoenol pyruvate to give 5-enolpyruvylshikimate-3-phosphate via the enzyme 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase. Glyphosate, the...

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Dihydrodipicolinate synthase

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4-Hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7, dihydrodipicolinate synthase, dihydropicolinate synthetase, dihydrodipicolinic acid synthase, L-aspartate-4-semialdehyde...

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Malate synthase

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Remington SJ (September 2003). "Structure of the Escherichia coli malate synthase G:pyruvate:acetyl-coenzyme A abortive ternary complex at 1.95 A resolution"...

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Citric acid cycle

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inhibits pyruvate dehydrogenase, isocitrate dehydrogenase, α-ketoglutarate dehydrogenase, and also citrate synthase. Acetyl-coA inhibits pyruvate dehydrogenase...

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Lipoyl synthase

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systems, and one of them is the pyruvate dehydrogenase complex. Studies that repressed the function of lipoyl synthase in Arabidopsis thaliana seeds showed...

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DAHP synthase

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D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating), DAH7-P synthase, DAHP synthase, DS-Co, DS-Mn, KDPH synthase, KDPH synthetase,...

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Oxaloacetic acid

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product being enol-oxaloacetate. It also arises from the condensation of pyruvate with carbonic acid, driven by the hydrolysis of ATP: CH3C(O)CO2− + HCO3−...

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Isochorismatase

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isochorismate pyruvate-hydrolase. Other names in common use include 2,3-dihydro-2,3-dihydroxybenzoate synthase, 2,3-dihydroxy-2,3-dihydrobenzoate synthase, and...

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Mitochondrial matrix

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in the matrix. The citric acid cycle is facilitated by pyruvate dehydrogenase, citrate synthase, aconitase, isocitrate dehydrogenase, α-ketoglutarate dehydrogenase...

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Anthranilate synthase

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anthranilate synthase (EC 4.1.3.27) catalyzes the chemical reaction chorismate + L-glutamine ⇌ {\displaystyle \rightleftharpoons } anthranilate + pyruvate + L-glutamate...

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Citramalate lyase

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synthetase, citramalic synthase, (S)-citramalate lyase, (+)-citramalate pyruvate-lyase, citramalate pyruvate lyase, (3S)-citramalate pyruvate-lyase, and...

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Unique properties of hyperthermophilic archaea

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process to start over. The only unique enzymes to this pathway are pyruvate synthase, pyruvate:water dikinase, and PEP carboxylase. Because so many of the steps...

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Ethyl pyruvate

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2013. Ethyl pyruvate protects rats from phosgene-induced pulmonary edema by inhibiting cyclooxygenase2 and inducible nitric oxide synthase expression....

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Fatty acid synthesis

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acetyl-CoA and NADPH through the action of enzymes called fatty acid synthases. This process takes place in the cytoplasm of the cell. Most of the acetyl-CoA...

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Gluconeogenesis

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gluconeogenesis may come from any non-carbohydrate sources that can be converted to pyruvate or intermediates of glycolysis (see figure). For the breakdown of proteins...

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Ferredoxin

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Oxidoreductase reactions (-500 mV) like the reaction carried out by pyruvate synthase. Ferredoxin can also be reduced by using NADH (-320 mV) or H 2 (-414...

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