Psychotic depression, also known as depressive psychosis, is a major depressive episode that is accompanied by psychotic symptoms.[3] It can occur in the context of bipolar disorder or major depressive disorder.[3] It can be difficult to distinguish from schizoaffective disorder, a diagnosis that requires the presence of psychotic symptoms for at least two weeks without any mood symptoms present.[3] Unipolar psychotic depression requires that psychotic symptoms occur during severe depressive episodes, although residual psychotic symptoms may also be present in between episodes (e.g., during remission, mild depression, etc.).[4][5][6][7][8][9] Diagnosis using the DSM-5 involves meeting the criteria for a major depressive episode, along with the criteria for "mood-congruent or mood-incongruent psychotic features" specifier.[10]
^"Psychotic Depression". WebMD.
^Dubovsky, Steven L.; Ghosh, Biswarup M.; Serotte, Jordan C.; Cranwell, Victoria (2021). "Psychotic Depression: Diagnosis, Differential Diagnosis, and Treatment". Psychotherapy and Psychosomatics. 90 (3): 160–177. doi:10.1159/000511348. PMID 33166960. S2CID 226296398.
^ abcHales E and Yudofsky JA, eds, The American Psychiatric Press Textbook of Psychiatry, Washington, DC: American Psychiatric Publishing, Inc., 2003
^Kupfer, D. J., Frank, E., & Phillips, M. L. (2012). Major depressive disorder: New clinical, neurobiological, and treatment perspectives. Lancet, 379(9820), 1045-1055
^Roca et al. (2014). Frequency and predictors of psychotic symptoms in a general population sample. Acta Psychiatrica Scandinavica, 129(4), 286-295
^García-Álvarez et al. (2013). Residual psychotic symptoms in depression: Prevalence and relationship to mood symptoms, anxiety symptoms, and treatment response. Acta Psychiatrica Scandinavica, 128(5), 375-382
^Lennox et al. (2010). Residual psychotic and depressive symptoms in a clinical trial for psychotic depression. Journal of Affective Disorders, 127(1-3), 243-248
^"ICD-10 Version:2019".
^https://cdn.website-editor.net/30f11123991548a0af708722d458e476/files/uploaded/DSM%2520V.pdf Archived 2023-03-22 at the Wayback Machine [bare URL PDF]
^American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington DC: American Psychiatric Association. ISBN 9780890425558.
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