Endogenous depression(melancholia) is an atypical subclass of major depressive disorder (clinical depression). It could be caused by genetic and biological factors.[1] Endogenous depression occurs due to the presence of an internal (cognitive, biological) stressor instead of an external (social, environmental) stressor.[2] Endogenous depression includes patients with treatment-resistant, non-psychotic, major depressive disorder, characterized by abnormal behavior of the endogenous opioid system but not the monoaminergic system.[3][4][5] Symptoms vary in severity, type, and frequency and can be attributed to cognitive, social, biological, or environmental factors that result in persistent feelings of sadness and distress. Since symptoms are due to a biological phenomenon, prevalence rates tend to be higher in older adults.[6] Due to this fact, biological-focused treatment plans are often used in therapy to ensure the best prognosis.[2]
Endogenous depression was part of the Kraepelinian dichotomy system.
^Matsunami, Katsufumi (2013). "The clinical meaning and academic significance of "endogenous depression" as an ideal type". Seishin Shinkeigaku Zasshi = Psychiatria et Neurologia Japonica. 115 (3): 267–276. ISSN 0033-2658. PMID 23691813.
^ abKramer, Thomas (2002). "Endogenous Versus Exogenous: Still Not the Issue". Medscape.
^Nyhuis PW, Specka M, Gastpar M (2006). "Does the antidepressive response to opiate treatment describe a subtype of depression?". European Neuropsychopharmacology. 16 (S4): S309. doi:10.1016/S0924-977X(06)70328-5. S2CID 54365563.
^Bodkin, JA; Zornberg, GL; Lukas, SE; Cole, JO (February 1995). "Harvard Medical School Clinical Study "Buprenorphine treatment of refractory depression."". Journal of Clinical Psychopharmacology. 15 (1): 49–57. doi:10.1097/00004714-199502000-00008. PMID 7714228.
^Bodkin, J. Alexander; Zornberg, Gwen L.; Lukas, Scott E.; Cole, Jonathan O. (February 1995). "Buprenorphine Treatment of Refractory Depression". Journal of Clinical Psychopharmacology. 15 (1): 49–57. doi:10.1097/00004714-199502000-00008. PMID 7714228.
^Watts, C. A. H. (1956-06-16). "The Incidence and Prognosis of Endogenous Depression". British Medical Journal. 1 (4980): 1392–1397. doi:10.1136/bmj.1.4980.1392. ISSN 0007-1447. PMC 1979411. PMID 13316166.
and 25 Related for: Endogenous depression information
Endogenousdepression (melancholia) is an atypical subclass of major depressive disorder (clinical depression). It could be caused by genetic and biological...
and endogenous variables in economic models Endogenous growth theory in economics Endogenous preferences in economics Endogenous money Endogenous depression...
The Great Depression (1929–1939) was a severe global economic downturn that affected many countries across the world. It became evident after a sharp decline...
of movement and mood. They attached the term to the concept of "endogenousdepression" (claimed to be caused by internal forces rather than environmental...
effectiveness of temazepam on the insomnia of patients with neurosis and endogenousdepression". Arzneimittel-Forschung. 19 (10): 1647–1652. PMID 4311716. Griffiths...
(ECS) is a biological system composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors...
hydrocodone, oxycodone and fentanyl; antagonist drugs such as naloxone; and endogenous peptides such as endorphins. The terms opiate and narcotic are sometimes...
Endorphins (contracted from endogenous morphine) are peptides produced in the brain that block the perception of pain and increase feelings of wellbeing...
the terms endogenousdepression, derived from Emil Kraepelin's use of the adjective to mean biological in origin, and reactive depression, more usually...
German-speaking countries, assumed masked depression (German: die larvierte Depression) to be endogenousdepression. The term was largely used in the 1970s...
chest with a blackjack and dagger. He was a teacher with severe endogenousdepression and suicidal ideation, later diagnosed with paranoia. Hours later...
Spermine Spermidine There is a distinction between endogenous and exogenous biogenic amines. Endogenous amines are produced in many different tissues (for...
Lithium ion (Li+) is used in psychiatry for the treatment of mania, endogenousdepression, and psychosis, and also for treatment of schizophrenia. Usually...
displaced by endogenous serotonin, indicating that receptor density or affinity is reduced. Dopamine transporter binding is not changed in depression. People...
ECT was, the guidelines concluded, an effective treatment for endogenousdepression. There was less certainty about its value in mania, and little evidence...
known as melancholia and is now known as clinical depression, major depression, or simply depression and commonly referred to as major depressive disorder...
strongly associated with melancholic depression, which is also referred to as endogenous or somatic depression. According to the diagnostic criteria...
"Clomipramine, tryptophan and lithium in combination for resistant endogenousdepression: seven case studies". The British Journal of Psychiatry. 151 (2):...
agonist as well as antagonist properties depending on the endogenous dopamine levels. When endogenous dopamine levels are high (as is hypothesized in schizophrenic...
Global Information