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Preiser disease information


Preiser disease
Scaphoid bone

Preiser disease, or (idiopathic) avascular necrosis of the scaphoid, is a rare condition where ischemia and necrosis of the scaphoid bone occurs without previous fracture. It is thought to be caused by repetitive microtrauma or side effects of drugs (e.g., steroids or chemotherapy) in conjunction with existing defective vascular supply to the proximal pole of the scaphoid. MRI coupled with CT and X-ray are the methods of choice for diagnosis.

Preiser's disease is initially treated by immobilising the wrist with a cast. However, in most cases the avascular scaphoid will start to collapse leading to degeneration within the wrist joints. This often requires surgical intervention to prevent the progression of arthris. Two commonly performed procedures are: 1. Proximal row carpectomy (PRC), which involves removing the first row of the carpal bones, i.e. the scaphoid, lunate and triquetrum. The wrist is immobilised in a cast for six weeks after the surgery and then physiotherapy is started. 2. Scaphoid excision and 4-corner fusion, which is a procedure consisting of the removal of the scaphoid and fixation of the remaining wrist bones with a plate (called a "spider plate") or wires in order to provide stability. The plate usually is left inside the patient's wrist, while the wires (usually K-wires) have to be removed in a second surgery. This procedure of partial wrist fusion allows for limited wrist movement, whereas total wrist fusion immobilizes the wrist permanently. Following surgery it can take several months for affected patients to regain strength. Unfortunately both of these operations are salvage procedures and movements in the wrist will be significantly reduced.[citation needed]

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Preiser disease

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discovered a route to a possible vaccine for the disease. "NTU: Academic Profile: Prof Peter Preiser". Research.ntu.edu.sg. Retrieved 17 November 2017...

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treatment for patients with wrist osteoarthritis.[citation needed] Preiser disease Koehler SM, Melone CP (2016). "Four-corner arthrodesis employing the...

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; Werner, O. (2006). "Avian Influenza". In Kamps, B. S.; Hoffman, C.; Preiser, W. (eds.). Influenza Report 2006. Paris: Flying Publisher. ISBN 978-3-924774-51-6...

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offers new vaccine hope". 19 December 2013. Gao X, Gunalan K, Yap SS, Preiser PR (2013). "Triggers of key calcium signals during erythrocyte invasion...

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Timm C.; Werner, Ortrud. Kamps, Bernd Sebastain; Hoffmann, Christian; Preiser, Wolfgang (eds.). "Influenza Report". Archived from the original on 10...

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PMID 28899424. Andersson MI, Maponga TG, Ijaz S, Barnes J, Theron GB, Meredith SA, Preiser W, Tedder RS (November 2013). "The epidemiology of hepatitis B virus infection...

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Rome, Byzantium, and China". Antiqvvs. 4 (1). Interview with Johannes Preiser-Kapeller: 41–45. Barrat, A.; et al. (2004). "The architecture of complex...

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septic shock. Preliminary observations. Intensive Care Med 18(5):309-11 Preiser JC, Lejeune P, Roman A, Carlier E, De Backer D, Leeman M, Kahn RJ, Vincent...

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Murphy, p.ix Leppard, pp. 4–6 Korsman NJ, van Zyl GU, Nutt L, Andersson MI, Preiser W (2012). Virology: an illustrated colour text. Churchill Livingstone....

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Plasmodium falciparum

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1001138. ISSN 1545-7885. PMC 3166167. PMID 21912516. Wilson RJ; Denny PW; Preiser PR; et al. (August 1996). "Complete gene map of the plastid-like DNA of...

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Glutaric aciduria type 1

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Psychiatry Neurosci. 18 (5): 235–44. PMC 1188544. PMID 8297922. Lovat, R.; Preiser, J. C. (2003). "Antioxidant therapy in intensive care". Current Opinion...

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HIV drug resistance

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Retrieved 30 October 2018. Nachega JB, Marconi VC, van Zyl GU, Gardner EM, Preiser W, Hong SY, Mills EJ, Gross R (April 2011). "HIV treatment adherence, drug...

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; Werner, O. (2006). "Avian Influenza". In Kamps, B. S.; Hoffman, C.; Preiser, W. (eds.). Influenza Report 2006. Paris, France: Flying Publisher....

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Anton Docher

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Press. ISBN 978-0-313-28767-1. Markovich, Nicholas C.; Wolfgang F. E. Preiser; Fred Gillette Sturm (1990). Pueblo style and regional architecture. Van...

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