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Chemical compound
Phytanic acid (or 3,7,11,15-tetramethyl hexadecanoic acid) is a branched chain fatty acid that humans can obtain through the consumption of dairy products, ruminant animal fats, and certain fish.[1] Western diets are estimated to provide 50–100 mg of phytanic acid per day.[2] In a study conducted in Oxford, individuals who consumed meat had, on average, a 6.7-fold higher geometric mean plasma phytanic acid concentration than did vegans.[3]
^Brown, P. J.; et al. (1993). "The determination of phytanic acid and phytol in certain foods and the application of this knowledge to the choice of suitable convenience foods for patients with Refsum's disease". Journal of Human Nutrition and Dietetics. 6: 295–305. doi:10.1111/j.1365-277x.1993.tb00375.x.
^Steinberg, D. Phytanic acid storage disease (Refsum's disease). In: Metabolic Basis of Inherited Disease. Edited by Stanbury JB, Wyngarden JB, Fredericksen DS, Goldstein JL, Brown MS, 5th edn. New York: McGraw Hill; 1983: 731-747.
^Allen, N. E.; Grace, P. B.; Ginn, A.; Travis, R. C.; Roddam, A. W.; Appleby, P. N.; Key, T. (2007). "Phytanic acid: Measurement of plasma concentrations by gas–liquid chromatography–mass spectrometry analysis and associations with diet and other plasma fatty acids". British Journal of Nutrition. 99 (3): 653–659. doi:10.1017/S000711450782407X. PMID 17868488.
Phytanicacid (or 3,7,11,15-tetramethyl hexadecanoic acid) is a branched chain fatty acid that humans can obtain through the consumption of dairy products...
recessive neurological disease that results in the over-accumulation of phytanicacid in cells and tissues. It is one of several disorders named after Norwegian...
break down dietary phytanicacid, which cannot undergo beta-oxidation due to its β-methyl branch, into pristanic acid. Pristanic acid can then acquire acetyl-CoA...
loss. Although humans cannot derive phytanicacid from chlorophyll, they can convert free phytol into phytanicacid. Thus, patients with Refsum disease...
such as rabbits and rodents. Great apes derive significant amounts of phytanicacid from the hindgut fermentation of plant materials. Monogastrics cannot...
with phytanicacid. In humans, pristanic acid is obtained from two sources: either directly from the diet or as the alpha oxidation product of phytanic acid...
mutations in the PEX family of genes. IRD is associated with deficient phytanicacid catabolism, as is adult Refsum disease, but they are different disorders...
reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanicacid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH...
the over-accumulation of very long chain fatty acids and branched chain fatty acids, such as phytanicacid. In addition, PBD-ZSD patients show deficient...
α-oxidation of phytanicacid β-oxidation of very-long-chain and polyunsaturated fatty acids biosynthesis of plasmalogens conjugation of cholic acid as part of...
(1): 62–63. Harkness, R. A.; Nicol, A. D. (December 1969). "Plasma Uric Acid Levels in Children". Archives of Disease in Childhood. 44 (238): 773–778...
g/mol, exact mass: 312.3028 u) may refer to: Arachidic acid, also called eicosanoic acidPhytanicacid This set index page lists chemical structure articles...
silage the phytanicacid found in their plasma lipids originates from chlorophyll. He then went on to discover other novel branched-chain acids in sheep...
Warter JM (Oct 1993). "A new peroxisomal disease with impaired phytanic and pipecolic acid oxidation". Neurology. 43 (10): 2044–2048. doi:10.1212/wnl.43...
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