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Physiome information


The physiome of an individual's or species' physiological state is the description of its functional behavior. The physiome describes the physiological dynamics of the normal intact organism and is built upon information and structure (genome, proteome, and morphome). The term comes from "physio-" (nature) and "-ome" (as a whole).

The concept of a physiome project was presented to the International Union of Physiological Sciences (IUPS) by its Commission on Bioengineering in Physiology in 1993. A workshop on designing the Physiome Project was held in 1997. At its world congress in 2001, the IUPS designated the project as a major focus for the next decade.[1] The project is led by the Physiome Commission of the IUPS.[2]

Other research initiatives related to the physiome include:

  • The EuroPhysiome Initiative
  • The NSR Physiome Project of the National Simulation Resource (NSR) at the University of Washington, supporting the IUPS Physiome Project
  • The Wellcome Trust Heart Physiome Project, a collaboration between the University of Auckland and the University of Oxford, part of the wider IUPS Physiome Project
  1. ^ Hunter, Peter J.; Thomas K. Borg (March 2003). "Integration from proteins to organs: the Physiome Project". Nature Reviews. Molecular Cell Biology. 4 (3): 237–243. doi:10.1038/nrm1054. PMID 12612642. S2CID 25185270.
  2. ^ "Welcome to the NSR Physiome Project". NSR Physiome Project. 28 October 2008. Retrieved 13 December 2008.

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Physiome

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The physiome of an individual's or species' physiological state is the description of its functional behavior. The physiome describes the physiological...

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Biomedicine

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functional relationships of the human genome, transcriptome, proteome, physiome and metabolome with the particular point of view of devising new technologies...

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Virtual Physiological Human

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came from the IUPS Physiome Project. The project was started in 1997 and represented the first worldwide effort to define the physiome through the development...

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CellML

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theoretically describe any mathematical model, it was originally created with the Physiome Project in mind, and hence used primarily to describe models relevant to...

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Systems biology

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the development of systems biology has become the international project Physiome.[citation needed] According to the interpretation of systems biology as...

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Physiology

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Molecular biology Metabolome Neurophysiology Pathophysiology Pharmacology Physiome American Physiological Society International Union of Physiological Sciences...

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Physiomics

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Physiomics is a systematic study of physiome in biology. Physiomics employs bioinformatics to construct networks of physiological features that are associated...

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Corpus luteum

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Biophys. 317 (2): 412–6. doi:10.1006/abbi.1995.1182. PMID 7893157. The IUPS Physiome Project --> Female Reproductive System – Cells Archived 2009-12-10 at the...

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Biomedical engineering

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Application of physics concepts, theories and methods to medicine or healthcare Physiome Biomedical Engineering and Instrumentation Program (BEIP) John Denis Enderle;...

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Phenotype

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Endophenotype Genotype–phenotype distinction Molecular phenotyping Phenomics Physiome Physiomics Race and genetics Systems biology List of omics topics in biology...

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Theca interna

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doi:10.1016/B978-0-12-801028-0.00226-9. ISBN 978-0-12-801028-0. The IUPS Physiome Project --> Female Reproductive System - Cells Archived December 10, 2009...

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International Union of Physiological Sciences

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2020 it established the journal Physiome to publish and curate mathematical models of physiological systems, the Physiome. Since 2010 IUPS has participated...

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Human Genome Project

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consortium investigating functional elements in human and model organism DNA Physiome HUGO Gene Nomenclature Committee – Committee for human gene name standards...

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Living Human Project

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algorithms for the human musculoskeletal apparatus used to create the physiome of the human musculoskeletal system. In 2006 the BEL was merged with Biomed...

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Denis Noble

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Physiological Sciences 1993–2001, he played a major role in launching the Physiome Project, an international project to use computer simulations to create...

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List of omics topics in biology

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Metabolome Volatilome Metallome Proteome Acetylome Obesidome Organome Phenome Physiome Connectome Synaptome Dynome Mechanome Regulome Researchsome Toponome Trialome...

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Physiologically based pharmacokinetic modelling

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systems biology models of metabolic pathways. They are also parallel to physiome models, but do not aim at modelling physiological functions beyond fluid...

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Patterson Companies

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rehabilitation part of Ireland-based DCC Healthcare (Days Healthcare, Physiomed and Ausmedic) in a move that increased Patterson Medical's revenue by...

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Medical image computing

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International Union for Physiological Sciences (IUPS) has been sponsoring the IUPS Physiome Project for more than a decade,. This is a worldwide public domain effort...

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Biosimulation

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project; funded by the 6th frame program of the European Union [2] NSR Physiome Project [3] Hepatosys Moreover, a few software tools already exist, which...

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Morphome

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Conference on Correlation Optics, Oleg V. Angelsky [pl]; Ed. Strategies for the physiome project. Bassingthwaighte JB. Ann Biomed Eng. 2000 Aug;28(8):1043-58. Review...

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Cardiophysics

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Important publications in medical physics Biomedicine Biomedical engineering Physiome Nanomedicine Books Kohl, Peter; Sachs, Frederick; Franz, Michael R. (2011)...

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Jeremy Levin

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Board Chair | BIO". www.bio.org. Retrieved 18 May 2021. "Jeremy Levin – Physiome Sciences – The Wall Street Transcript". The Wall Street Transcript. 12...

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Macroethics and microethics

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1981 Bassingthwaighte J.B. The macro-ethics of genomics to health: the physiome project. Comptes Rendus Biologies. 2003 Oct–Nov;326(10–11):1105–10. Herkert...

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Systems geology

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actively developed in many other areas, such as biology and medicine (EuroPhysiome) opening the prospect of widely shared concepts, structures and implementations...

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Network theory of aging

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of aging on multiple levels of biological organization contributed to a physiome view, from genes to organisms, predicting lifespans based on scaling laws...

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List of Intelligent Systems for Molecular Biology keynote speakers

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Chromosome Evolution Peter Hunter Computational Physiology and the IUPS Physiome Project Satoru Miyano Computational Challenges for Gene Networks Ewan Birney...

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