Physical oncology (PO) is defined as the study of the role of mechanical signals in a cancerous tumor. The mechanical signals can be forces, pressures ("pull", "push" and "shear" designating the forces / pressures that push, pull or are tangential). If we generalize we will speak of "stress field" and "stress tensor".[1][2][3]
A cancerous tumor (or "solid tumor" in the jargon of oncologists to differentiate them from hematological malignancies) is an organ consisting of two tissues: in the center the cancerous tumor proper and around the ExtraCellular Matrix (ECM), sometimes called stroma, chorion or connective tissue. The concept of connective tissue is interesting because it defines a tissue that travels the entire organism (except the brain) and is a preferred transmitter of mechanical signals. But for the cancer organ - isolated from this connective system - we prefer the term ECM.
The cancerous tissue is derived from a normal tissue of the body: breast cancer arises from a cancerous transformation of the normal mammary glandular tissue. It looks more or less like the original tissue: it is said that it is more or less differentiated; poorly differentiated it has a microscopic appearance that is far from normal tissue and is then "poorly prognostic", will make more metastases and will be more difficult to treat.
We are only considering cancers derived from "epithelia", that is to say the tissue that covers the organs in their interfaces with air, liquids ... or the outside world. Epithelial cells are contiguous and polarized. More than 90% of cancers (breast, prostate, colon / rectum, bronchi, pancreas, etc.) arise from these epithelia after a long process of cancerization.
^Jonietz, Erika (2012-11-21). "Mechanics: The forces of cancer". Nature. 491 (7425): S56–S57. doi:10.1038/491s56a. PMID 23320288.
^"The Forces of Cancer". The Scientist. Retrieved 2017-11-16.
^Wang, Karin; Cai, Li-Heng; Lan, Bo; Fredberg, Jeffrey J (2016-01-28). "Hidden in the mist no more: physical force in cell biology". Nature Methods. 13 (2): 124–125. doi:10.1038/nmeth.3744. ISSN 1548-7105. PMC 4861038. PMID 26820546.
Physicaloncology (PO) is defined as the study of the role of mechanical signals in a cancerous tumor. The mechanical signals can be forces, pressures...
Oncology is a branch of medicine that deals with the study, treatment, diagnosis, and prevention of cancer. A medical professional who practices oncology...
The Physical Sciences in Oncology Network (PS-ON) is a network of centers and projects set up by the National Institutes of Health (NIH) National Cancer...
field of oncology and palliative care is a continuously evolving and developing specialty, both in malignant and non-malignant diseases. Physical therapy...
The history of cancer describes the development of the field of oncology and its role in the history of medicine. In 2016, a 1.7 million year old osteosarcoma...
Exercise is physical activity that enhances or maintains fitness and overall health. It is performed for various reasons, including weight loss or maintenance...
World Health Organization's definition Health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity...
susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty...
American Society of Clinical Oncology provide guidelines for the follow-up of colon cancer. A medical history and physical examination are recommended...
Molecular oncology is an interdisciplinary medical specialty at the interface of medicinal chemistry and oncology that refers to the investigation of...
Desmoplastic small round cell tumor Liposarcoma Lists of diseases List of oncology-related terms [1] National Cancer Institute "Defining Cancer". National...
Asia-Pacific Journal of Oncology Nursing Asian Journal of Andrology Asian Journal of Neurosurgery Asian Journal of Oncology Asian Journal of Pediatric...
American Society of Clinical Oncology made this recommendation based on various cancers. See American Society of Clinical Oncology, "Five Things Physicians...
with misophonia generally have strong negative feelings, thoughts, and physical reactions to specific sounds, which the literature calls "trigger sounds"...
The CRUK/MRC Oxford Institute for Radiation Oncology is a research institute of the Department of Oncology. The Centre for Evidence-Based Medicine is a...
and their spousal caregivers: the dyadic effects of physical and mental health". Psycho-Oncology. 20 (12): 1353–7. doi:10.1002/pon.1855. PMC 3020233....
other therapies such as warm baths, local therapy with heating pads, and physical therapy. An alternative form of medicine called ayurveda is also used for...
Global Information