Syndrome causing muscle loss not entirely reversible
"Wasting syndrome" redirects here. For the process by which a debilitating disease causes muscle and fat tissue to "waste" away, see wasting.
Medical condition
Cachexia
Other names
Wasting syndrome
Processes and mechanisms related to cancer-associated cachexia
Specialty
Oncology, Internal Medicine, Physical Medicine and Rehabilitation
Symptoms
sudden weight loss, altered eating signals
Prognosis
very poor
Frequency
1%
Deaths
1.5 to 2 million people a year
Cachexia (/kəˈkɛksiə/[1]) is a complex syndrome associated with an underlying illness, causing ongoing muscle loss that is not entirely reversed with nutritional supplementation. A range of diseases can cause cachexia, most commonly cancer, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease, and AIDS. Systemic inflammation from these conditions can cause detrimental changes to metabolism and body composition. In contrast to weight loss from inadequate caloric intake, cachexia causes mostly muscle loss instead of fat loss. Diagnosis of cachexia can be difficult due to the lack of well-established diagnostic criteria. Cachexia can improve with treatment of the underlying illness but other treatment approaches have limited benefit. Cachexia is associated with increased mortality and poor quality of life.
The term is from Greek κακός kakos 'bad' and ἕξις hexis 'condition'.
^"Cachexia | Definition of Cachexia by Lexico". Lexico Dictionaries | English. Archived from the original on November 8, 2019.
Cachexia (/kəˈkɛksiə/) is a complex syndrome associated with an underlying illness, causing ongoing muscle loss that is not entirely reversed with nutritional...
starvation and can be reversed with nutritional therapy. In contrast, cachexia is a wasting syndrome caused by an underlying disease such as cancer that...
dietary needs of each animal have to be considered to avoid causing harm. Cachexia Malnutrition "Emaciation". Medical-Dictionary.TheFreeDictionary.com. Retrieved...
to changes in muscle synthesis signalling pathways. It is distinct from cachexia, in which muscle is degraded through cytokine-mediated degradation, although...
development for a variety of other indications, including treatment of cachexia, Duchenne muscular dystrophy, muscle atrophy or sarcopenia, and stress...
caused by reduction in calorific intake or increase in exercise is called cachexia and may be a symptom of a serious medical condition. Intentional weight...
cancer cachexia. Nishie, Kenichi; Nishie, Tomomi; Sato, Seiichi; Hanaoka, Masayuki (September 2023). "Update on the treatment of cancer cachexia". Drug...
ways to reduce the risks of developing these deficiencies. Starvation Cachexia Emaciation Kwashiorkor Protein poisoning Appleton & Vanbergen, Metabolism...
Dysregulation of appetite contributes to anorexia nervosa, bulimia nervosa, cachexia, overeating, and binge eating disorder. A limited or excessive appetite...
been investigated in human studies for the treatment of osteoporosis, cachexia (wasting syndrome), benign prostatic hyperplasia, stress urinary incontinence...
an endogenous pyrogen, is able to induce fever, apoptotic cell death, cachexia, and inflammation, inhibit tumorigenesis and viral replication, and respond...
under development by Helsinn Healthcare SA for the treatment of cancer cachexia and anorexia. Anamorelin significantly increases plasma levels of growth...
punishment for slaves. 2007–2008 world food price crisis Anorexia mirabilis Cachexia Global Hunger Index Starvation mode Famine scales Hunger strike List of...
including cancer, AIDS, and heart failure can cause muscle loss known as cachexia. Myopathies have been modeled with cell culture systems of muscle from...
diseases such as cancer and AIDS induce a body wasting syndrome called cachexia, which is notable for the severe muscle atrophy seen. Other syndromes or...
FACES syndrome is a syndrome of unique facial features (facies), anorexia, cachexia, eye and skin anomalies. It is a rare disease and estimated to occur in...
clinical trials in individuals with AIDS and cancer, but not rheumatoid cachexia. Clinical trials with Juven for AIDS have also demonstrated improvements...
name Durabolin). Nandrolone esters are used in the treatment of anemias, cachexia (muscle wasting syndrome), osteoporosis, breast cancer, and for other indications...
used mainly as an appetite stimulant to treat wasting syndromes such as cachexia. It is also used to treat breast cancer and endometrial cancer, and has...
(age-related muscle atrophy), osteoporosis, and weight loss due to cancer cachexia, but development for these indications was discontinued. The drug is taken...
people with cancer cachexia are encouraged to engage in physical exercise. Due to various factors, some individuals with cancer cachexia have a limited capacity...
inflammatory state that leads to ongoing muscle loss and weakness, known as cachexia. Some cancers, such as Hodgkin's disease, leukemias, and liver or kidney...
peas) can assist in controlling the loss of muscle mass. Anorexia Atrophy Cachexia Superior mesenteric artery syndrome Weight loss UNICEF/WHO/The World Bank...
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