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Phospholipid scramblase 1 information


PLSCR1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPLSCR1, MMTRA1B, phospholipid scramblase 1
External IDsOMIM: 604170; MGI: 893575; HomoloGene: 41418; GeneCards: PLSCR1; OMA:PLSCR1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021105
NM_001363872
NM_001363874

NM_011636

RefSeq (protein)

NP_066928
NP_001350801
NP_001350803

NP_035766

Location (UCSC)Chr 3: 146.52 – 146.54 MbChr 9: 92.13 – 92.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phospholipid scramblase 1 (PL scramblase 1) is an enzyme that in humans is encoded by the PLSCR1 gene.[5][6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000188313 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032369 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhou Q, Zhao J, Stout JG, Luhm RA, Wiedmer T, Sims PJ (August 1997). "Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids". J Biol Chem. 272 (29): 18240–4. doi:10.1074/jbc.272.29.18240. PMID 9218461.
  6. ^ "Entrez Gene: PLSCR1 phospholipid scramblase 1".

and 22 Related for: Phospholipid scramblase 1 information

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Phospholipid scramblase

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Scramblase is a protein responsible for the translocation of phospholipids between the two monolayers of a lipid bilayer of a cell membrane. In humans...

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Phospholipid scramblase 1

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Phospholipid scramblase 1 (PL scramblase 1) is an enzyme that in humans is encoded by the PLSCR1 gene. PLSCR1 has been shown to interact with: CPSF6, Epidermal...

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Lipid bilayer

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The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules. These membranes are flat sheets that form a...

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Flippase

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transporters. Scramblases are energy-independent and transport lipids in both directions. In organisms, the cell membrane consists of a phospholipid bilayer...

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PLSCR2

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Phospholipid scramblase 2, also known as Ca2+-dependent phospholipid scramblase 2, is a protein that in humans is encoded by the PLSCR2 gene. scramblase...

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Epidermal growth factor receptor

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Nanjundan M, Pike LJ, Wiedmer T, Sims PJ (May 2002). "Plasma membrane phospholipid scramblase 1 is enriched in lipid rafts and interacts with the epidermal growth...

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PLSCR4

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Phospholipid scramblase 4, also known as Ca2+-dependent phospholipid scramblase 4, is a protein that is encoded in humans by the PLSCR4 gene. Scramblase...

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Cell membrane

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cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining...

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PLSCR3

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Phospholipid scramblase 3 is an enzyme that in humans is encoded by the PLSCR3 gene (abbreviated to PLS3 in this section). Like the other phospholipid...

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SLPI

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Monteiro RC, Hocini H, Madrid R, Benichou S (2009-01-01). "The phospholipid scramblases 1 and 4 are cellular receptors for the secretory leukocyte protease...

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Fluid mosaic model

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layer consisting primarily of amphipathic phospholipids) in which protein molecules are embedded. The phospholipid bilayer gives fluidity and elasticity to...

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Lipid

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on the cytosolic side and the activation of scramblases, which scramble the orientation of the phospholipids. After this occurs, other cells recognize the...

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Red blood cell

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energy-dependent manner. Additionally, there are also "scramblase" proteins that move phospholipids in both directions at the same time, down their concentration...

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Tubby protein

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Finn RD, Sims PJ, Wiedmer T, Biegert A, Söding J (January 2009). "Phospholipid scramblases and Tubby-like proteins belong to a new superfamily of membrane...

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Annexin A5 affinity assay

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protein known as scramblase. Phagocytic white blood cells express a receptor that can bind to and detect the negatively charged phospholipids on the apoptotic...

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Membrane transport

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resource is the Transporter Classification database Cellular transport Scramblases Lodish; et al. (2005). Biología celular y molecular (Buenos Aires: Médica...

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Anoctamin 6

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may play a role in syncytia formation during COVID-19 infection. Phospholipid scramblase GRCh38: Ensembl release 89: ENSG00000177119 – Ensembl, May 2017...

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List of unusual biological names

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accumulation of target transcripts/proteins. Salvador Scramblase An enzyme that "scrambles" phospholipids between the inside and outside of the cell membrane...

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Platelet

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turns on scramblase, which moves negatively charged phospholipids from the inner to the outer platelet membrane surface. These phospholipids then bind...

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Microvesicle

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space between cells) and in many types of body fluids. Delimited by a phospholipid bilayer, microvesicles can be as small as the smallest EVs (30 nm in...

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Membrane curvature

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as flippases, or removed to discourage curvature by proteins such as scramblases. When asymmetric lipid compositions are present and the membrane is unable...

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PRKCD

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RasGRP3 in response to phorbol esters". Mol. Pharmacol. 66 (1): 76–84. doi:10.1124/mol.66.1.76. PMID 15213298. S2CID 5774849. Leitges M, Gimborn K, Elis...

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