Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Phenethyl isothiocyanate (PEITC) is a naturally occurring isothiocyanate whose precursor, gluconasturtiin is found in some cruciferous vegetables,[1] especially watercress.
PEITC has been studied for its potential for chemoprevention of cancers,[2][3] such as prostate cancer.[4]
In terms of biosynthesis, PEITC is produced from gluconasturtiin by the action of the enzyme myrosinase.
^"Dictionary of Cancer Terms: PEITC". National Cancer Institute.
^Cheung, KL; Kong, AN (2010). "Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention". The AAPS Journal. 12 (1): 87–97. doi:10.1208/s12248-009-9162-8. PMC 2811646. PMID 20013083.
^Kwon, Ki Han; Xu, Changjiang; Keum, Young-Sam; Khor, Tin Oo; Kim, Jung-Hwan; Huang, Mou-Tuan; Reddy, Bandaru S.; Li, Wenge; Kong, Ah-Ng Tony (2007). "Natural dietary phytochemicals: a promising future for cancer prevention and treatment of earlier lesion". Cancer: Disease Progression and Chemoprevention: 109–126.
^Wang, LG; Chiao, JW (2010). "Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review)". International Journal of Oncology. 37 (3): 533–9. doi:10.3892/ijo_00000702. PMID 20664922.
and 27 Related for: Phenethyl isothiocyanate information
Phenethylisothiocyanate (PEITC) is a naturally occurring isothiocyanate whose precursor, gluconasturtiin is found in some cruciferous vegetables, especially...
Gluconasturtiin is the precursor to phenethylisothiocyanate Glucoraphanin is the precursor to sulforaphane Phenyl isothiocyanate, is used for amino acid sequencing...
is due to its degradation by the plant enzyme myrosinase into phenethylisothiocyanate, which is toxic to many organisms. Gluconasturtiin is named from...
cabbage juices: comparison with the effects of indole-3-carbinol and phenethylisothiocyanate". Br J Nutr. 105 (6): 816–26. doi:10.1017/S0007114510004526. PMID 21092375...
which changes the glucosinolate, so that it cannot be converted to isothiocyanate. A second is that the glucosinates are quickly broken down, forming...
inhibitors. Noncompetitive inhibitors of CYP2C9 include nifedipine, phenethylisothiocyanate, medroxyprogesterone acetate and 6-hydroxyflavone. It was indicated...
of phenethylisothiocyanate (R)-4-(methylsulfinyl)butylglucosinolate (glucoraphanin) is the precursor of (R)-4-(methylsulfinyl)butyl isothiocyanate (sulforaphane)...
(September 2010). "Prostate cancer chemopreventive activity of phenethylisothiocyanate through epigenetic regulation (review)". International Journal...
(September 2010). "Prostate cancer chemopreventive activity of phenethylisothiocyanate through epigenetic regulation (review)". International Journal...
trans-resveratrol and hesperetin (tRES-HESP), mangiferin, allyl isothiocyanate, phenethylisothiocyanate, sulforaphane, and bardoxolone methyl, and MG scavengers...
inhibitors. These include sulphorphane, indole-3-carbinol, and phenethylisothiocyanates, found in broccoli, kale, and watercress, and epigallocatecehin-3-gallate...
Shin JA, Choi ES, Cho NP, Kim HM, Leem DH, Cho SD (July 2012). "β-Phenethylisothiocyanate induces death receptor 5 to induce apoptosis in human oral cancer...
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