Phenelzine, sold under the brand name Nardil, among others, is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is primarily used as an antidepressant and anxiolytic.[3] Along with tranylcypromine and isocarboxazid, phenelzine is one of the few non-selective and irreversible MAOIs still in widespread clinical use.[4]
Synthesis of phenelzine was first described by Emil Votoček and Otakar Leminger in 1932.[5][6]
^"Phenelzine (Nardil) Use During Pregnancy". Drugs.com. 3 March 2020. Retrieved 11 July 2020.
^Anvisa (31 March 2023). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 4 April 2023). Archived from the original on 3 August 2023. Retrieved 16 August 2023.
^"Phenelzine: MedlinePlus Drug Information". medlineplus.gov. Retrieved 27 October 2023.
^Sidhu G, Marwaha R (2023). "Phenelzine". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 32119395. Retrieved 23 November 2023.
^Budavari S, O'Neil, Smith A, Heckelman PE, Kinneary JF (1996). "Phenelzine". The Merck Index (12th ed.). Whitehouse Station: Merck & Co. 7181.
^Votoček E, Leminger O (1932). "Sur la β-phenoéthylhydrazine" [On the [preparation and properties of] β-phenoethylhydrazine]. Collection of Czechoslovak Chemical Communications (in French). 4: 271–281. doi:10.1135/cccc19320271.
Phenelzine, sold under the brand name Nardil, among others, is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class...
been caused by serotonin syndrome from the drug interaction between the phenelzine she was taking prior to her hospital visit, and the pethidine administered...
antidepressant phenelzine and is responsible for its elevation of GABA concentrations. PEH may contribute to phenelzine's anxiolytic effects. Phenelzine Parent...
anxiety, but they come with many unwanted side effects and are rarely used. Phenelzine was shown to be a good treatment option, but its use is limited by dietary...
when cyclobenzaprine was taken with the serotonergic drugs duloxetine or phenelzine. These substances may interact with cyclobenzaprine: Central nervous system...
phenylethylidenehydrazine (and drugs that metabolize to it, such as phenelzine), ethanolamine-O-sulfate (EOS), and L-cycloserine. Certain members of...
Marmite should be avoided if a person takes a MAOI antidepressant, such as phenelzine (Nardil) or tranylcypromine (Parnate), as yeast extracts interact adversely...
use during breastfeeding. Ginseng also has adverse drug reactions with phenelzine, and a potential interaction has been reported with imatinib, resulting...
received treatment with irreversible monoamine oxidase inhibitors such as phenelzine, tranylcypromine or isocarboxazid within the past 30 days and those with...
restaurant, and in June 2007, on his doctor's advice, he stopped taking phenelzine, his primary antidepressant drug. His depression recurred, and he tried...
(SSRIs), and somewhat less effective than the older, irreversible MAOIs phenelzine and tranylcypromine. In terms of tolerability, however, moclobemide was...
amitriptyline may reduce depression, but mianserin, fluoxetine, fluvoxamine, and phenelzine sulfate showed no effect. Omega-3 fatty acid may ameliorate suicidality...
psychopharmacology, psychiatric units in general hospitals, combined amitriptyline/phenelzine poisoning, and drug addiction. In 1967, Jarecki became involved with the...
depression Paxil (paroxetine) – an antidepressant of the SSRI class Nardil (Phenelzine) – an antidepressant of the MAOI class used to treat depression Orap (Pimozide)...
MDMA in combination with certain monoamine oxidase inhibitors, such as phenelzine (Nardil), tranylcypromine (Parnate), or moclobemide (Aurorix, Manerix)...
camylofin, bendazol, triafungin, phenacemide, lorcainide, phenindione, phenelzine and cyclopentolate.[citation needed] In the crime drama Breaking Bad,...
inhibitors within 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Drinking alcohol can increase...
and increased emotions, especially in large doses. Unlike MAOIs such as phenelzine, harmine and harmaline are reversible and selective meaning they do not...
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