Phenacyl chloride information

Phenacyl chloride
Names
	Preferred IUPAC name 2-Chloro-1-phenylethan-1-one
	Other names 2-Chloro-1-phenylethanone; α-Chloroacetophenone; 2-Chloroacetophenone; Chloromethyl phenyl ketone; Phenyl chloromethyl ketone; CN; Weeping gas; Mace
Identifiers
CAS Number	532-27-4 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL105712 ;
ChemSpider	10303 ;
ECHA InfoCard	100.007.757
IUPHAR/BPS	6285;
PubChem CID	10757;
UNII	88B5039IQG ;
CompTox Dashboard (EPA)	DTXSID9020293 ;
	InChI InChI=1S/C8H7ClO/c9-6-8(10)7-4-2-1-3-5-7/h1-5H,6H2;
	SMILES c1ccc(cc1)C(=O)CCl;
Properties
Chemical formula	C8H7ClO
Molar mass	154.59 g·mol−1
Appearance	white to gray crystalline solid
Odor	pungent and irritating
Density	1.324 g/cm3
Melting point	54 to 56 °C (129 to 133 °F; 327 to 329 K)
Boiling point	244.5 °C (472.1 °F; 517.6 K)
Solubility in water	insoluble
Vapor pressure	0.005 mmHg (20 °C)
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Combustible
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H300, H311+H331, H315, H318, H334, H335
Precautionary statements	P280, P301+P310+P330, P302+P352+P312, P304+P340+P311, P305+P351+P338+P310
NFPA 704 (fire diamond)	3 1 0
Flash point	88 °C (190 °F; 361 K)
	Lethal dose or concentration (LD, LC):
LCLo (lowest published)	417 mg/m3 (rat, 15 min); 600 mg/m3 (mouse, 15 min); 465 mg/m3 (rabbit, 20 min); 490 mg/m3 (guinea pig, 30 min); 159 mg/m3 (human, 20 min); 850 mg/m3 (human, 10 min)
	NIOSH (US health exposure limits):
PEL (Permissible)	TWA 0.3 mg/m3 (0.05 ppm)
REL (Recommended)	TWA 0.3 mg/m3 (0.05 ppm)
IDLH (Immediate danger)	15 mg/m3
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Phenacyl chloride, also commonly known as chloroacetophenone, is a substituted acetophenone. It is a useful building block in organic chemistry. Apart from that, it has been historically used as a riot control agent, where it is designated CN.^[5] It should not be confused with cyanide, another agent used in chemical warfare, which has the chemical structure CN⁻. Chloroacetophenone is thermally stable, and is the only tear agent that is distillable at ambient conditions.

^ Verma, K.S. Cengage Physical Chemistry Part 1 Archived 2021-05-06 at the Wayback Machine, Illustration 5.65
^ ^a ^b ^c ^d ^e ^f ^g NIOSH Pocket Guide to Chemical Hazards. "#0119". National Institute for Occupational Safety and Health (NIOSH).
^ "alpha-Chloroacetophenone". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
^ GHS: GESTIS 037810
^ Treudler, R.; Tebbe, B.; Blume-Peytavi, U.; Krasagakis, K.; Orfanos, C. E. (1999). "Occupational contact dermatitis due to 2-chloracetophenone tear gas". British Journal of Dermatology. 140 (3): 531–534. doi:10.1046/j.1365-2133.1999.02724.x. PMID 10233281. S2CID 45123933.

[1] Verma, K.S. Cengage Physical Chemistry Part 1 Archived 2021-05-06 at the Wayback Machine, Illustration 5.65

[PGCH-2] ^ ^a ^b ^c ^d ^e ^f ^g NIOSH Pocket Guide to Chemical Hazards. "#0119". National Institute for Occupational Safety and Health (NIOSH).

[3] "alpha-Chloroacetophenone". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).

[4] GHS: GESTIS 037810

[doi10.1046/j.1365-2133.1999.02724.x-5] Treudler, R.; Tebbe, B.; Blume-Peytavi, U.; Krasagakis, K.; Orfanos, C. E. (1999). "Occupational contact dermatitis due to 2-chloracetophenone tear gas". British Journal of Dermatology. 140 (3): 531–534. doi:10.1046/j.1365-2133.1999.02724.x. PMID 10233281. S2CID 45123933.

Phenacyl chloride information

and 28 Related for: Phenacyl chloride information

Phenacyl chloride

Chloroacetyl chloride

Tear gas

Geraniol

Oxime

Rosemary

Mustard plant

Clove

Thyme

Turmeric

Allyl isothiocyanate

Phenacyl group

Piperine

Wasabi

Long pepper

Chemosis

Formaldehyde

Vanillin

Paracetamol

Ruta graveolens

Cannabis

Stevia rebaudiana

Monarda fistulosa

CS gas

Methyl salicylate

Onion

Alkyl nitrite

Camphora officinarum

Names


Preferred IUPAC name 2-Chloro-1-phenylethan-1-one
Other names 2-Chloro-1-phenylethanone α-Chloroacetophenone 2-Chloroacetophenone Chloromethyl phenyl ketone Phenyl chloromethyl ketone CN Weeping gas^[1] Mace
Identifiers
CAS Number	532-27-4^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL105712^N
ChemSpider	10303^N
ECHA InfoCard	100.007.757
IUPHAR/BPS	6285
PubChem CID	10757
UNII	88B5039IQG^Y
CompTox Dashboard (EPA)	DTXSID9020293
InChI InChI=1S/C8H7ClO/c9-6-8(10)7-4-2-1-3-5-7/h1-5H,6H2
SMILES c1ccc(cc1)C(=O)CCl
Properties
Chemical formula	C₈H₇ClO
Molar mass	154.59 g·mol⁻¹
Appearance	white to gray crystalline solid^[2]
Odor	pungent and irritating^[2]
Density	1.324 g/cm³
Melting point	54 to 56 °C (129 to 133 °F; 327 to 329 K)
Boiling point	244.5 °C (472.1 °F; 517.6 K)
Solubility in water	insoluble
Vapor pressure	0.005 mmHg (20 °C)^[2]
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Combustible^[2]
GHS labelling:^[4]
Pictograms
Signal word	Danger
Hazard statements	H300, H311+H331, H315, H318, H334, H335
Precautionary statements	P280, P301+P310+P330, P302+P352+P312, P304+P340+P311, P305+P351+P338+P310
NFPA 704 (fire diamond)	3 1 0
Flash point	88 °C (190 °F; 361 K)
Lethal dose or concentration (LD, LC):
LC_Lo (lowest published)	417 mg/m³ (rat, 15 min) 600 mg/m³ (mouse, 15 min) 465 mg/m³ (rabbit, 20 min) 490 mg/m³ (guinea pig, 30 min) 159 mg/m³ (human, 20 min) 850 mg/m³ (human, 10 min)^[3]
NIOSH (US health exposure limits):
PEL (Permissible)	TWA 0.3 mg/m³ (0.05 ppm)^[2]
REL (Recommended)	TWA 0.3 mg/m³ (0.05 ppm)^[2]
IDLH (Immediate danger)	15 mg/m³^[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references