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Chloroacetyl chloride information


Not to be confused with Acetyl chloride or Chloroacetic acid.
Chloroacetyl chloride
Skeletal formula
ball-and-stick model
Names
Preferred IUPAC name
Chloroacetyl chloride
Other names
2-Chloroacetyl chloride
Chloroacetic acid chloride
Chloroacetic chloride
Monochloroacetyl chloride
Identifiers
CAS Number
  • 79-04-9 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:34624
ChEMBL
  • ChEMBL3187685
ChemSpider
  • 13856283 ☒N
ECHA InfoCard 100.001.065 Edit this at Wikidata
EC Number
  • 201-171-6
KEGG
  • C14859 checkY
PubChem CID
  • 6577
RTECS number
  • AO6475000
UNII
  • K5UML06YUO checkY
UN number 1752
CompTox Dashboard (EPA)
  • DTXSID4026472 Edit this at Wikidata
InChI
  • InChI=1S/C2H2Cl2O/c3-1-2(4)5/h1H2 ☒N
    Key: VGCXGMAHQTYDJK-UHFFFAOYSA-N ☒N
  • InChI=1/C2H2Cl2O/c3-1-2(4)5/h1H2
    Key: VGCXGMAHQTYDJK-UHFFFAOYAB
SMILES
  • C(C(=O)Cl)Cl
Properties
Chemical formula
 C2H2Cl2O
Molar mass 112.94 g·mol−1
Appearance Colorless to yellow liquid
Density 1.42 g/mL
Melting point −22 °C (−8 °F; 251 K)
Boiling point 106 °C (223 °F; 379 K)
Solubility in water
 Reacts
Vapor pressure 19 mmHg (20°C)[1]
Hazards
GHS labelling:
Pictograms
 GHS05: CorrosiveGHS06: ToxicGHS08: Health hazardGHS09: Environmental hazard
Signal word
 Danger
Hazard statements
 H301, H311, H314, H331, H372, H400
Precautionary statements
 P260, P261, P264, P270, P271, P273, P280, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P311, P312, P314, P321, P322, P330, P361, P363, P391, P403+P233, P405, P501
NFPA 704 (fire diamond)
[2]
NFPA 704 four-colored diamondHealth 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gasFlammability 0: Will not burn. E.g. waterInstability 1: Normally stable, but can become unstable at elevated temperatures and pressures. E.g. calciumSpecial hazards (white): no code
3
0
1
Flash point noncombustible[1]
NIOSH (US health exposure limits):
PEL (Permissible)
 none[1]
REL (Recommended)
 TWA 0.05 ppm (0.2 mg/m3)[1]
IDLH (Immediate danger)
 N.D.[1]
Safety data sheet (SDS) Oxford MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Chloroacetyl chloride is a chlorinated acyl chloride. It is a bifunctional compound, making it a useful building block chemical.

  1. ^ a b c d e NIOSH Pocket Guide to Chemical Hazards. "#0120". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ "OSHA Occupational Chemical Database". Occupational Safety and Health Administration (OSHA).

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precious material: Acylation of the amino group of (−)-H-3 with chloroacetyl chloride, followed by treatment of the product H-3a with potassium t-butoxide...

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