Pentapeptide repeats are a family of sequence motifs found in multiple tandem copies in protein molecules.[2][3] Pentapeptide repeat proteins are found in all species, but they are found in many copies in cyanobacterial genomes. The repeats were first identified by Black and colleagues in the hglK protein.[4] The later Bateman et al. showed that a large family of related pentapeptide repeat proteins existed.[3] The function of these repeats is uncertain in most proteins. However, in the MfpA protein a DNA gyrase inhibitor it has been suggested that the pentapeptide repeat structure mimics the structure of DNA.[5] The repeats form a regular right handed four sided beta helix structure known as the Rfr-fold.
^Ni S, Sheldrick GM, Benning MM, Kennedy MA (January 2009). "The 2 Å resolution crystal structure of HetL, a pentapeptide repeat protein involved in regulation of heterocyst differentiation in the cyanobacterium Nostoc sp. strain PCC 7120". J. Struct. Biol. 165 (1): 47–52. doi:10.1016/j.jsb.2008.09.010. PMID 18952182.
^ abBateman A, Murzin AG, Teichmann SA (June 1998). "Structure and distribution of pentapeptide repeats in bacteria". Protein Sci. 7 (6): 1477–80. doi:10.1002/pro.5560070625. PMC 2144021. PMID 9655353.
^Black K, Buikema WJ, Haselkorn R (November 1995). "The hglK gene is required for localization of heterocyst-specific glycolipids in the cyanobacterium Anabaena sp. strain PCC 7120". J. Bacteriol. 177 (22): 6440–8. doi:10.1128/jb.177.22.6440-6448.1995. PMC 177493. PMID 7592418.
^Hegde SS, Vetting MW, Roderick SL, et al. (June 2005). "A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA". Science. 308 (5727): 1480–3. Bibcode:2005Sci...308.1480H. doi:10.1126/science.1110699. PMID 15933203. S2CID 20194294.
and 15 Related for: Pentapeptide repeat information
Pentapeptiderepeats are a family of sequence motifs found in multiple tandem copies in protein molecules. Pentapeptiderepeat proteins are found in all...
Look up pentapeptide in Wiktionary, the free dictionary. Pentapeptide may refer to: An oligopeptide formed from five amino acids Pentapeptiderepeat This...
rather than stabilizing cleavage complexes. These include YacG and pentapeptiderepeat proteins, such as QnrB1 and MfpA; these protein inhibitors also confer...
Examples of short repeats exhibiting ordered structures include the three-residue collagen repeat or the five-residue pentapeptiderepeat that forms a beta...
proteins to associate, similar to coiled coil segments. Members of the pentapeptiderepeat family have been shown to possess a quadrilateral beta-helix structure...
Examples of short repeats exhibiting ordered structures include the three-residue collagen repeat or the five-residue pentapeptiderepeat that forms a beta...
an RNA recognition motif, a Merozoite surface protein (MSP-1), a pentapeptiderepeat MXKDX, and a domain of unknown function (DUF1387). These domains...
EP3-2, EP3-4), and two genes that encode proteins with internal pentapeptide GPEET repeats (GPEET2). EP1 is a 141 amino acids protein and EP2 is a 129 AA...
A. G.; Teichmann, S. A. (1998). "Structure and distribution of pentapeptiderepeats in bacteria". Protein Science. 7 (6): 1477–80. doi:10.1002/pro.5560070625...
Nastainczyk W, Kunau WH, Schliebs W (Sep 2001). "The di-aromatic pentapeptiderepeats of the human peroxisome import receptor PEX5 are separate high affinity...
of the protein is the tetratricopeptide repeat (TPR) motif recognition site, the conserved MEEVD pentapeptide, that is responsible for the interaction...
in the accumulation of polyprenyl diphosphate-N-acetylmuramic acid-(pentapeptide)-N-acetyl-glucosamine, thought to be the peptidoglycan intermediated...
comprises four repeats homologous to the ligand-binding portion of the LDL receptor with six conserved cysteine residues and a pentapeptide, DGSDE, which...
oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. Nucleoporin 153 has a mass of 153 kDA (hence...
encodes a pentapeptide AHH(A/E)A. The Tx segment of adult fsTnT in avian orders of Galliformes and Craciformes contains 7-9 H(A/E)AAH repeats that possess...
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