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Pacific Biosciences of California, Inc. (aka PacBio) is an American biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation.[2][3][failed verification] PacBio has two principal sequencing platforms: single-molecule real-time sequencing (SMRT), based on the properties of zero-mode waveguides and sequencing by binding (SBB) chemistry, which uses native nucleotides and scarless incorporation for DNA binding and extension.[4][5]
^"Pacific Biosciences Form 8-K". U.S. Securities and Exchange Commission. February 15, 2024.
^bloomberg.com https://www.bloomberg.com/businessweek/globalbiz/content/dec2009/gb2009123_706120.htm. {{cite web}}: Missing or empty |title= (help)[permanent dead link]
^Brakmann, Susanne (April 5, 2010). "A ribosome in action". Nature. 464 (7291): 987–988. doi:10.1038/464987a. PMID 20393548. S2CID 1742990.
^Rhoads, Anthony; Au, Kin Fai (October 1, 2015). "PacBio Sequencing and Its Applications". Genomics, Proteomics & Bioinformatics. 13 (5): 278–289. doi:10.1016/j.gpb.2015.08.002. ISSN 1672-0229. PMC 4678779. PMID 26542840.
122°09′03″W / 37.4787°N 122.1507°W / 37.4787; -122.1507 (headquarters) PacificBiosciences of California, Inc. (aka PacBio) is an American biotechnology company...
introduced different approaches in their third-generation sequencers. PacificBiosciences sequencers utilize a method called Single-molecule real-time (SMRT)...
which a primed template molecule is bound. This approach is used by PacificBiosciences. Larger DNA molecules (up to tens of thousands of base pairs) can...
into the DNA strand, leaving an unmodified DNA strand. According to PacificBiosciences (PacBio), the SMRT technology developer, this methodology allows...
Illumina, Knome, Sequenom, 454 Life Sciences, PacificBiosciences, Complete Genomics, Helicos Biosciences, GE Global Research (General Electric), Affymetrix...
diverse cohort of individuals. The HPRC samples were sequenced using PacificBiosciences (PacBio) high-fidelity (HiFi) and Oxford Nanopore Technologies (ONT)...
next generation sequencing platforms: comparison of Ion Torrent, PacificBiosciences and Illumina MiSeq sequencers". BMC Genomics. 13: 341. doi:10.1186/1471-2164-13-341...
Clarisonic, or PacificBioscience Laboratories, Inc., was a company based in Redmond, Washington that produced the Clarisonic line of skin care devices...
in Nucleic Acids Research in 2010. It was later commercialized by PacificBiosciences in 2018 and made available on Sequel II and Revio long-read sequencing...
sequencing technologies, including PacBio RSII and PacBio Sequel by PacificBiosciences, and Nanopore MinION, GridION, PromethION by Oxford Nanopore Technologies...
Pharmaceuticals, Inc. 2008–2012: Director, GenProbe, Inc. 2012: Director, PacificBioSciences, Inc. 2015: Founded Boragen, LLC with Stephen Benkovic, Gerry Fink...
$900 million convertible bond investment in DNA-sequencing company PacificBiosciences of California, Bloomberg reported that SoftBank was planning to invest...
produced draft assemblies of A. candida. The most recent one, using PacificBiosciences sequencing technology, produced an genome assembly of 38.96 megabases...
third-generation sequencing platforms including PacBio (Sequel I/II) by PacificBiosciences and MinION, PromethION by Oxford Nanopore Technology. As compared...
St. Joseph Health Michael Hunkapiller (born 1948) United States PacificBiosciences 2020 2023 Moungi Bawendi (born 1961) United States "for synthesis...
next generation sequencing platforms: comparison of Ion Torrent, PacificBiosciences and Illumina MiSeq sequencers". BMC Genomics. 13: 341. doi:10.1186/1471-2164-13-341...
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US$200.5 million (2023)