PTPN7 information

PTPN7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1ZC0, 2A3K, 2GP0, 2GPH, 2HVL, 2QDC, 2QDM, 2QDP, 3D42, 3D44, 3O4S, 3O4T, 3O4U
Identifiers
Aliases	PTPN7, BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI, protein tyrosine phosphatase, non-receptor type 7, protein tyrosine phosphatase non-receptor type 7
External IDs	OMIM: 176889 MGI: 2156893 HomoloGene: 15411 GeneCards: PTPN7
Gene location (Human)
Chr.	Chromosome 1 (human)
End	202,161,588 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	135,073,055 bp
RNA expression pattern
	Top expressed in
	lymph node; ; bone marrow cells; ; appendix; ; thymus; ; blood; ; spleen; ; putamen; ; caudate nucleus; ; gallbladder; ; monocyte;
	Top expressed in
	thymus; ; bone marrow; ; spleen; ; pharynx; ; neck; ; yolk sac; ; jejunum; ; ileum; ; white adipose tissue; ; lung;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein tyrosine phosphatase activity; phosphatase activity; protein binding; phosphoprotein phosphatase activity; hydrolase activity;
Cellular component	cytoplasmic side of plasma membrane; cytoskeleton; cytoplasm; cytosol; nucleoplasm;
Biological process	dephosphorylation; peptidyl-tyrosine dephosphorylation; protein dephosphorylation; cellular response to cytokine stimulus;
	Sources:Amigo / QuickGO
Orthologs
	5778
	320139
	ENSG00000143851
	ENSMUSG00000031506
	P35236
	Q8BUM3
NM_001199797; NM_002832; NM_080588; NM_080589; NM_001364877;
	NM_001364878
	NM_177081; NM_001356382
	NP_001186726; NP_002823; NP_542155; NP_001351806; NP_001351807
	NP_796055; NP_001343311
	Wikidata
View/Edit Human	View/Edit Mouse

Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143851 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031506 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Adachi M, Sekiya M, Isobe M, Kumura Y, Ogita Z, Hinoda Y, Imai K, Yachi A (September 1992). "Molecular cloning and chromosomal mapping of a human protein-tyrosine phosphatase LC-PTP". Biochem Biophys Res Commun. 186 (3): 1607–15. doi:10.1016/S0006-291X(05)81592-X. PMID 1510684.
^ "Entrez Gene: PTPN7 protein tyrosine phosphatase, non-receptor type 7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143851 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031506 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1510684-5] Adachi M, Sekiya M, Isobe M, Kumura Y, Ogita Z, Hinoda Y, Imai K, Yachi A (September 1992). "Molecular cloning and chromosomal mapping of a human protein-tyrosine phosphatase LC-PTP". Biochem Biophys Res Commun. 186 (3): 1607–15. doi:10.1016/S0006-291X(05)81592-X. PMID 1510684.

[entrez-6] "Entrez Gene: PTPN7 protein tyrosine phosphatase, non-receptor type 7".

PTPN7 information

and 7 Related for: PTPN7 information

PTPN7

List of distinct cell types in the adult human body

Chromosome 1

MAPK1

MAPK3

PTPN5

PTPRR