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PHEX information


PHEX
Identifiers
AliasesPHEX, HPDR, HPDR1, HYP, HYP1, LXHR, PEX, XLH, phosphate regulating endopeptidase homolog, X-linked, phosphate regulating endopeptidase homolog X-linked
External IDsOMIM: 300550 MGI: 107489 HomoloGene: 37310 GeneCards: PHEX
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000444
NM_001282754

NM_011077

RefSeq (protein)

NP_000435
NP_001269683

NP_035207

Location (UCSC)Chr X: 22.03 – 22.49 MbChr X: 155.95 – 156.2 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphate-regulating endopeptidase homolog X-linked also known as phosphate-regulating gene with homologies to endopeptidases on the X chromosome or metalloendopeptidase homolog PEX is an enzyme that in humans is encoded by the PHEX gene.[5][6] This gene contains 18 exons and is located on the X chromosome.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000102174 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000057457 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Francis F, Hennig S, Korn B, Reinhardt R, De Jong P, Poustka A, et al. (October 1995). "A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium". Nature Genetics. 11 (2): 130–136. doi:10.1038/ng1095-130. PMID 7550339. S2CID 6424732.
  6. ^ Grieff M, Mumm S, Waeltz P, Mazzarella R, Whyte MP, Thakker RV, Schlessinger D (February 1997). "Expression and cloning of the human X-linked hypophosphatemia gene cDNA". Biochemical and Biophysical Research Communications. 231 (3): 635–639. doi:10.1006/bbrc.1997.6153. PMID 9070861.

and 21 Related for: PHEX information

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Phex

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Phex is a peer-to-peer file sharing client for the gnutella network, released under the terms of the GNU General Public License, so Phex is free software...

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PHEX

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substrate for PHEX. In the absence of functional PHEX in the mouse model (Hyp) of X-linked hypophosphatemia (XLH), and in human XLH where PHEX activity is...

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Merkle tree

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Retrieved 23 September 2018. Arne Babenhauserheide (7 Jan 2007). "Phex 3.0.0 released". Phex. Retrieved 23 September 2018. "DC++'s feature list". dcplusplus...

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Osteomalacia

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(e.g. TNAP/TNSALP/ALPL enzyme degrading the pyrophosphate inhibition, and PHEX enzyme degrading the osteopontin inhibition). The Stenciling Principle for...

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Phosphate diabetes

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hypophosphatemic rickets (XLH), this disease is caused by a mutation in the X-linked PHEX (phosphate regulating endopeptidase X-linked) gene, which encodes for a protein...

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JoJolion

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that automatically track down their target using their breathing. The A. Phex Brothers are twin Rock Humans who pose as street performers. Having played...

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Gnutella

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Proprietary No 5.55.1 (November 15, 2007; 16 years ago (2007-11-15)) [±] GnucDNA Phex Java GPL No 3.4.2.116 (February 1, 2009; 15 years ago (2009-02-01)) [±] Original...

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Fibroblast growth factor 23

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doi:10.1093/ndt/17.6.958. PMID 12032180. Quarles LD (July 2003). "FGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralization"...

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List of P2P protocols

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Freenet Freenet, Frost Gnutella Cabos, Envy, Gnucleus, gtk-gnutella, iphex, Phex, Shareaza, WireShare Acquisition, BearShare, FileScope, iMesh, LimeWire,...

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Metalink

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not in repo not in repo not in repo not in repo KGet Yes Yes Yes Yes No Phex not in repo not in repo not in repo not in repo SmartFTP not in repo not...

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I2P

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after its release date. I2Phex is a port of the popular Gnutella client Phex to I2P. It is stable and fairly functional. Tahoe-LAFS has been ported to...

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Osteocyte

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shown to function in mineral metabolism, as well as other molecules such as PHEX, DMP-1, MEPE, and FGF-23, which are highly expressed by osteocytes and regulate...

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Timeline of file sharing

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of files at once, and search across the entire network for files. March – Phex (formerly FURI) Gnutella client released. May – UMG v. MP3.com causes My...

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Osteopontin

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whose actions may modulate the mineralization-inhibiting function of OPN. PHEX (phosphate-regulating endopeptidase homolog X-linked) is one such enzyme...

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Tubulopathy

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↑Ca, ↑PO4, ↑Glycosuria X-linked dominant hypophosphatemic rickets [307800 PHEX Xp22.2-p22.1 XD Growth retardation, rachitic and osteomalacic bone disease...

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Oncogenic osteomalacia

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induced osteomalacia from XHR and ADHR. If necessary, genetic testing for PHEX (phosphate regulating gene with homologies to endopeptidase on the X-chromosome)...

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MEPE

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36172–80. doi:10.1074/jbc.M003622200. PMID 10967096. Quarles LD (2003). "FGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralization"...

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Hypophosphatasia

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TNAP/TNSALP/ALPL enzyme degrading the pyrophosphate inhibition of mineralization, and PHEX enzyme degrading the osteopontin inhibition of mineralization). The Stenciling...

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Jacques Perconte

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wiiijing 2002 esz, SD 4min. 2002 xsz, SD 4min. 2001 I'm a slave for you 2001 Phex, SD 145min. 2001 Tempo e pause, SD 60min. 2001 matre zias e imaji imacul...

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Phacelia exilis

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org: 239433 Open Tree of Life: 3870270 Plant List: tro-16200573 PLANTS: PHEX POWO: urn:lsid:ipni.org:names:282580-2 Tropicos: 16200573 WFO: wfo-0001066982...

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List of OMIM disorder codes

Last Update:

Hypophosphatasia, infantile; 241500; ALPL Hypophosphatemia, X-linked; 307800; PHEX Hypophosphatemic rickets with hypercalciuria; 241530; SLC34A3 Hypophosphatemic...

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