negative regulation of protein homotetramerization
peroxisome transport along microtubule
negative regulation of protein binding
negative regulation of DNA-binding transcription factor activity
microtubule anchoring
protein import into peroxisome matrix
protein import into peroxisome matrix, substrate release
protein transport
negative regulation of transcription, DNA-templated
protein homooligomerization
protein import into peroxisome matrix, translocation
transport
protein targeting to peroxisome
protein import into peroxisome matrix, docking
protein ubiquitination
protein-containing complex assembly
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
5195
56273
Ensembl
ENSG00000142655
ENSMUSG00000028975
UniProt
O75381
Q9R0A0
RefSeq (mRNA)
NM_004565
NM_019781
RefSeq (protein)
NP_004556
NP_062755
Location (UCSC)
Chr 1: 10.47 – 10.63 Mb
Chr 4: 149.04 – 149.18 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Peroxisomal membrane anchor protein (Pex14p) conserved region
Identifiers
Symbol
Pex14_N
Pfam
PF04695
InterPro
IPR006785
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
Peroxisomal membrane protein PEX14 is a protein that in humans is encoded by the PEX14 gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000142655 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000028975 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Fransen M, Terlecky SR, Subramani S (Jul 1998). "Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein import". Proceedings of the National Academy of Sciences of the United States of America. 95 (14): 8087–92. Bibcode:1998PNAS...95.8087F. doi:10.1073/pnas.95.14.8087. PMC 20933. PMID 9653144.
Peroxisomal membrane protein PEX14 is a protein that in humans is encoded by the PEX14 gene. This gene encodes an essential component of the peroxisomal...
a peroxisomal membrane protein pex14 to form a complex. When the pex5 protein with bound cargo interacts with the pex14 membrane protein, the complex induces...
have mutations in the PEX1, PEX2, PEX3, PEX5, PEX6, PEX10, PEX12, PEX13, PEX14, PEX16, PEX19, or PEX26 genes. In almost all cases, patients have mutations...
original on 20 February 2020. Retrieved 2 August 2020. "ELM - Detail for LIG_Pex14_2". elm.eu.org. Archived from the original on 21 February 2020. Retrieved...
Wxxx[FY] motif indicates that TMEM267 could be involved in the interaction of Pex14 with Pex5 proteins. Overall, TMEM267 is most likely found in the cytoplasm...
Zellweger syndrome. PEX5 has been shown to interact with PEX12, PEX13 and PEX14. ENSG00000288217 GRCh38: Ensembl release 89: ENSG00000139197, ENSG00000288217...
Lazam A, Jung M, Sattler M, Schliebs W, Erdmann R (January 2014). "A novel Pex14 protein-interacting site of human Pex5 is critical for matrix protein import...
on chromosome 2 next to KIAA1841 PEX13 has been shown to interact with PEX14, PEX5 and PEX19. GRCh38: Ensembl release 89: ENSG00000162928 – Ensembl,...
Global Information
