PBX2 information

PBX2
Identifiers
Aliases	PBX2, G17, HOX12, PBX2MHC, PBX homeobox 2
External IDs	OMIM: 176311; MGI: 1341793; HomoloGene: 48115; GeneCards: PBX2; OMA:PBX2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	32,190,202 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,816,374 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; granulocyte; ; right ovary; ; spleen; ; body of uterus; ; pituitary gland; ; left ovary; ; anterior pituitary; ; left uterine tube;
	Top expressed in
	genital tubercle; ; tail of embryo; ; granulocyte; ; mandibular prominence; ; maxillary prominence; ; somite; ; saccule; ; germ layer; ; ectoderm; ; otic vesicle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; transcription factor binding; chromatin binding; protein binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; transcription regulator complex;
Biological process	proximal/distal pattern formation; regulation of transcription, DNA-templated; embryonic limb morphogenesis; transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	5089
	18515
ENSG00000224952; ENSG00000237344; ENSG00000236353; ENSG00000232005; ENSG00000225987;
	ENSG00000206315; ENSG00000204304
	ENSMUSG00000034673
	P40425
	O35984
	NM_002586
	NM_017463
	NP_002577
	NP_059491
	Wikidata
View/Edit Human	View/Edit Mouse

Pre-B-cell leukemia transcription factor 2 is a protein that in humans is encoded by the PBX2 gene.^[5]^[6]

^ ^a ^b ^c ENSG00000237344, ENSG00000236353, ENSG00000232005, ENSG00000225987, ENSG00000206315, ENSG00000204304 GRCh38: Ensembl release 89: ENSG00000224952, ENSG00000237344, ENSG00000236353, ENSG00000232005, ENSG00000225987, ENSG00000206315, ENSG00000204304 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034673 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sugaya K, Fukagawa T, Matsumoto K, Mita K, Takahashi E, Ando A, Inoko H, Ikemura T (Sep 1994). "Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3". Genomics. 23 (2): 408–19. doi:10.1006/geno.1994.1517. PMID 7835890.
^ "Entrez Gene: PBX2 pre-B-cell leukemia homeobox 2".

[refGRCh38Ensembl-1] ENSG00000237344, ENSG00000236353, ENSG00000232005, ENSG00000225987, ENSG00000206315, ENSG00000204304 GRCh38: Ensembl release 89: ENSG00000224952, ENSG00000237344, ENSG00000236353, ENSG00000232005, ENSG00000225987, ENSG00000206315, ENSG00000204304 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034673 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7835890-5] Sugaya K, Fukagawa T, Matsumoto K, Mita K, Takahashi E, Ando A, Inoko H, Ikemura T (Sep 1994). "Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3". Genomics. 23 (2): 408–19. doi:10.1006/geno.1994.1517. PMID 7835890.

[entrez-6] "Entrez Gene: PBX2 pre-B-cell leukemia homeobox 2".

PBX2 information

and 14 Related for: PBX2 information

PBX2

List of human transcription factors

Homeobox

PBX3

Evolution of cetaceans

Methylammonium lead halide

PBX1

Plumbylene

PAX8

NOTCH3

MEIS1

Notch 4

HOXA9

TLX1