Condition in which bones are abnormally hardened, with elevated density
Not to be confused with Osteoporosis or Pachyostosis.
Medical condition
Osteosclerosis
Sclerosis of the bones of the pelvis due to prostate cancer metastases
Specialty
Medical genetics
Osteosclerosis is a disorder that is characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone. Plain radiographs are a valuable tool for detecting and classifying osteosclerotic disorders.[1][2] It can manifest in localized or generalized osteosclerosis. Localized osteosclerosis can be caused by Legg–Calvé–Perthes disease, sickle-cell disease and osteoarthritis among others. Osteosclerosis can be classified in accordance with the causative factor into acquired and hereditary.[2][1]
^ abEL-Sobky TA, Elsobky E, Sadek I, Elsayed SM, Khattab MF (2016). "A case of infantile osteopetrosis: The radioclinical features with literature update". Bone Rep. 4: 11–16. doi:10.1016/j.bonr.2015.11.002. PMC 4926827. PMID 28326337.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ abCite error: The named reference Ihde was invoked but never defined (see the help page).
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