Lipodystrophy syndromes are a group of genetic or acquired disorders in which the body is unable to produce and maintain healthy fat tissue.[1][2] The medical condition is characterized by abnormal or degenerative conditions of the body's adipose tissue. A more specific term, lipoatrophy (lipo is Greek for 'fat', and dystrophy is Greek for 'abnormal or degenerative condition'), is used when describing the loss of fat from one area (usually the face). This condition is also characterized by a lack of circulating leptin which may lead to osteosclerosis. The absence of fat tissue is associated with insulin resistance, hypertriglyceridemia, non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome.[3][4]
^Phan J, Reue K (January 2005). "Lipin, a lipodystrophy and obesity gene". Cell Metabolism. 1 (1): 73–83. doi:10.1016/j.cmet.2004.12.002. PMID 16054046.
^"UCLA/VA Researchers discover fat gene". Archived from the original on 2018-10-06. Retrieved 2017-06-15.
^Brown RJ, Araujo-Vilar D, Cheung PT, Dunger D, Garg A, Jack M, Mungai L, Oral EA, Patni N, Rother KI, von Schnurbein J, Sorkina E, Stanley T, Vigouroux C, Wabitsch M, Williams R, Yorifuji T (December 2016). "The Diagnosis and Management of Lipodystrophy Syndromes: A Multi-Society Practice Guideline". The Journal of Clinical Endocrinology and Metabolism. 101 (12): 4500–4511. doi:10.1210/jc.2016-2466. PMC 5155679. PMID 27710244.
^Ajluni N, Meral R, Neidert AH, Brady GF, Buras E, McKenna B, DiPaola F, Chenevert TL, Horowitz JF, Buggs-Saxton C, Rupani AR, Thomas PE, Tayeh MK, Innis JW, Omary MB, Conjeevaram H, Oral EA (May 2017). "Spectrum of disease associated with partial lipodystrophy: lessons from a trial cohort". Clinical Endocrinology. 86 (5): 698–707. doi:10.1111/cen.13311. PMC 5395301. PMID 28199729.
Lipodystrophy syndromes are a group of genetic or acquired disorders in which the body is unable to produce and maintain healthy fat tissue. The medical...
Cellulite or gynoid lipodystrophy (GLD) is the herniation of subcutaneous fat within fibrous connective tissue that manifests as skin dimpling and nodularity...
as Cushingoid facies. Moon face is a type of corticosteroid-induced lipodystrophy along with "buffalo hump", which in one study occurred in 47% of the...
Centrifugal lipodystrophy is a skin condition characterized by areas of subcutaneous fat loss that slowly enlarge.: 496–7 Lipodystrophy List of cutaneous...
Acquired generalized lipodystrophy (AGL), also known as Lawrence syndrome and Lawrence–Seip syndrome, is a rare skin condition that appears during childhood...
mandibular hypoplasia (a small lower jaw), deafness, tightening of the skin, lipodystrophy (a reduction in fat under the skin), low testosterone levels in males...
dyslipidemia. It has been approved in Japan for metabolic disorders including lipodystrophy and in the United States as replacement therapy to treat the complications...
the two pathologies. Marfanoid–progeroid–lipodystrophy syndrome (MPL), also referred to as Marfan lipodystrophy syndrome (MFLS), is a variant of MFS in...
syndrome Mandibuloacral dysplasia with type A lipodystrophy Mandibuloacral dysplasia with type B lipodystrophy Marbach-Rustad progeroid syndrome Marshall-Smith...
Familial partial lipodystrophy, also known as Köbberling–Dunnigan syndrome, is a rare genetic metabolic condition characterized by the loss of subcutaneous...
Dunnigan-type familial partial lipodystrophy, also known as FPLD Type II and abbreviated as (FPLD2), is a rare monogenic form of insulin resistance characterized...
hormone (GHRH) which is used in the treatment of HIV-associated lipodystrophy, approved initially in 2010. It is produced and developed by Theratechnologies...
Localized lipodystrophy is a skin condition characterized by the loss of subcutaneous fat localized to sites of insulin injection.: 497 Lipodystrophy List...
Berardinelli-Seip congenital lipodystrophy, Dunnigan familial partial lipodystrophy) and acquired (e.g., HIV-related lipodystrophy in people treated with highly...
Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE) syndrome is an autosomal recessive disorder that presents...
skin emphasizing a progeroid appearance, and mild midface hypoplasia. Lipodystrophy, or the absence of adipose tissue beneath the skin, is another common...
the entire body's adipose tissue is lipodystrophy. Radermecker RP, Piérard GE, Scheen AJ (2007). "Lipodystrophy reactions to insulin: effects of continuous...
medicine and rehabilitation, General surgery, Plastic surgery Diagnostic method Based on symptoms Differential diagnosis Lipodystrophy, venous insufficiency...
Global Information