Ornidazole is an antibiotic used to treat protozoan infections.[1]: 1368 A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohydrin.[2]
Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated;[1]: 1368 however there are concerns of lower relative efficacy.[3]
It was first introduced for treating trichomoniasis before being recognized for its broad anti-protozoan and anti-anaerobic-bacterial capacities.[4]: 1261 has also been investigated for use in Crohn's disease after bowel resection.[5]
^ abcdKuhlmann FM, Fleckenstein JM (2017-01-01). "157 - Antiparasitic Agents". In Cohen J, Powderly WG, Opal SM (eds.). Infectious Diseases (Fourth ed.). Elsevier. pp. 1345–1372.e2. doi:10.1016/B978-0-7020-6285-8.00157-X. ISBN 978-0-7020-6285-8.
^Sharma S, Anand N (January 1997). "Chapter 17 - Nitroheterocycles". In Sharma S, Anand N (eds.). Pharmacochemistry Library. Approaches to Design and Synthesis of Antiparasitic Drugs. Vol. 25. Elsevier. p. 428. doi:10.1016/S0165-7208(97)80039-6. ISBN 9780444894762.
^Nagel JL, Aronoff DM (January 2015). "28 - Metronidazole". In Bennett JE, Dolin R, Blaser MJ (eds.). Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases (Eighth ed.). Content Repository Only!. p. 356. ISBN 978-1-4557-4801-3.
^Wilcox MH (January 2017), "147 - Nitroimidazoles, Metronidazole, Ornidazole and Tinidazole; and Fidaxomicin", in Cohen J, Powderly WG, Opal SM (eds.), Infectious Diseases (Fourth ed.), Elsevier, pp. 1261–1263.e1, ISBN 978-0-7020-6285-8
^Rutgeerts P, Van Assche G, Vermeire S, D'Haens G, Baert F, Noman M, et al. (April 2005). "Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial". Gastroenterology. 128 (4): 856–861. doi:10.1053/j.gastro.2005.01.010. PMID 15825069.
Ornidazole is an antibiotic used to treat protozoan infections.: 1368 A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction...
Ofloxacin and ornidazole J01RA10 Ciprofloxacin and metronidazole J01RA11 Ciprofloxacin and tinidazole J01RA12 Ciprofloxacin and ornidazole J01RA13 Norfloxacin...
include metronidazole, tinidazole, nimorazole, dimetridazole, pretomanid, ornidazole, megazol, and azanidazole. Drugs based on 2-nitroimidazoles include benznidazole...
Metronidazole, or a related drug such as Tinidazole, Secnidazole or Ornidazole, is used to destroy amoebae that have invaded tissue. Several drugs are...
medication is used such as metronidazole, tinidazole, secnidazole or ornidazole. No Burkholderia mallei Glanders No Gnathostoma spinigerum and Gnathostoma...
also been used as a form of treatment. Drugs such as secnidazole and ornidazole have been used as well, but are not available in the United States. Dientamoeba...
medication is used such as metronidazole, tinidazole, secnidazole or ornidazole. The World Health Organisation and Infectious Disease Society of America...
used as eye drops and ear drops and is available in combination with ornidazole. Resistance to ofloxacin and other fluoroquinolones may evolve rapidly...
anti-amoebic compounds, this often includes the use of Metronidazole, Ornidazole, Chloroquine, Secnidazole, Nitazoxanide and Tinidazole. Tinidazole may...
Entamoeba infections. Anti-parasitic medications such as metronidazole and ornidazole are generally used to treat human infections. Combination therapies such...
trichomonas parasites. Examples include: furazolidone nifuratel nimorazole ornidazole tinidazole usnic acid Antitrichomonal+Agents at the U.S. National Library...
hydrogels with covalently bound silver nanoparticles can effectively release ornidazole to treat infections. Dextran conjugated with oligolactide chains through...
this list, which follows the WHO version. QP51AA02 Tinidazole QP51AA03 Ornidazole QP51AA04 Azanidazole QP51AA05 Propenidazole QP51AA06 Nimorazole QP51AA07...
in vitro study compared the effects of dehydroemetine, metronidazole, ornidazole, and secnidazole on Entamoeba histolytica. Metronidazole was found to...