This article's factual accuracy may be compromised due to out-of-date information. The reason given is: Per the 2021 update of the WHO classification, almost any oligoastrocytoma can be classified as either astrocytoma or oligodendroglioma via genetic testing. Oligoastrocytoma is reserved for tumors with incomplete diagnostics. Please help update this article to reflect recent events or newly available information.(August 2021)
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Medical condition
Oligoastrocytoma
A oligoastrocytoma on CT
Specialty
Neuro-oncology
Oligoastrocytomas are a subset of brain tumors that present with an appearance of mixed glial cell origin, astrocytoma and oligodendroglioma.[1] However, the term "Oligoastrocytoma" is now considered obsolete by the National Comprehensive Cancer Network[2] stating "the term should no longer be used as such morphologically ambiguous tumors can be reliably resolved into astrocytomas and oligodendrogliomas with molecular testing."
These types of glial cells that become cancerous are involved with insulating and regulating the activity of neuron cells in the central nervous system. Often called a "mixed glioma", about 2.3% of all reported brain tumors are diagnosed as oligoastrocytoma.[citation needed] The median age of diagnosis is 42.5. [citation needed]
Oligoastrocytomas, like astrocytomas and oligodendrogliomas, can be divided into low-grade and anaplastic variant, the latter characterized by high cellularity, conspicuous cytologic atypism, mitotic activity and, in some cases, microvascular proliferation and necrosis.
However, lower grades can have less aggressive biology.
These are largely supratentorial tumors of adulthood that favor the frontal and temporal lobes.
Oligoastrocytomas are a subset of brain tumors that present with an appearance of mixed glial cell origin, astrocytoma and oligodendroglioma. However...
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was confirmed publicly that the tumour was classified as a cancerous oligoastrocytoma, and after a rapid deterioration of his health, further surgery took...
common in classic oligodendrogliomas than in either astrocytomas or oligoastrocytomas. In one study, classic oligodendrogliomas showed 1p loss in 35 of...
astrocytoma, oligodendroglioma, anaplastic oligodendroglioma, oligoastrocytoma, anaplastic oligoastrocytoma, and secondary glioblastoma. Mutations in IDH1 are often...
glioma: develop in or around the optic nerve Mixed gliomas, such as oligoastrocytomas, contain cells from different types of glia Gliomas are further categorised...
various glial tumor cells; for example, oligodendrogliomas, mixed oligoastrocytomas, glioblastomas, and pleomorphic xanthoastrocytomas. Gemistocytes are...
glioblastoma and other diffuse gliomas (astrocytomas, oligodendrogliomas and oligoastrocytomas), and is a useful positive diagnostic marker of these brain tumors...
common in classic oligodendrogliomas than in either astrocytomas or oligoastrocytomas. In one study, classic oligodendrogliomas showed 1p loss in 35 of...
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