Novobiocin, also known as albamycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which has recently been identified as a subjective synonym for S. spheroides[1] a member of the class Actinomycetia. Other aminocoumarin antibiotics include clorobiocin and coumermycin A1.[2] Novobiocin was first reported in the mid-1950s (then called streptonivicin).[3][4]
^Lanoot B, Vancanneyt M, Cleenwerck I, Wang L, Li W, Liu Z, Swings J (May 2002). "The search for synonyms among streptomycetes by using SDS-PAGE of whole-cell proteins. Emendation of the species Streptomyces aurantiacus, Streptomyces cacaoi subsp. cacaoi, Streptomyces caeruleus and Streptomyces violaceus". International Journal of Systematic and Evolutionary Microbiology. 52 (Pt 3): 823–9. doi:10.1099/00207713-52-3-823. PMID 12054245.
^da Silva Eustáquio A (2004). Biosynthesis of aminocoumarin antibiotics in Streptomyces: Generation of structural analogues by genetic engineering and insights into the regulation of antibiotic production (Ph.D. thesis). Universität Tübingen.
^Hoeksema H, Johnson JL, Hinman JW (December 1955). "Structural studies on streptonivicin, a new antibiotic". Journal of the American Chemical Society. 77 (24): 6710–6711. doi:10.1021/ja01629a129.
^Smith CG, Dietz A, Sokolski WT, Savage GM (February 1956). "Streptonivicin, a new antibiotic. I. Discovery and biologic studies". Antibiotics & Chemotherapy. 6 (2): 135–142. PMID 24543916.
Novobiocin, also known as albamycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which has recently been identified...
35 °C, and white or tan in colour. Occasionally, strains are resistant to novobiocin and may be confused with other resistant species (e.g. S. saprophyticus)...
susceptibility to the antibiotic novobiocin. S. saprophyticus is novobiocin-resistant, whereas S. epidermidis is novobiocin-sensitive. Staphylococcus saprophyticus...
DNA gyrase is the target of many antibiotics, including nalidixic acid, novobiocin, albicidin, and ciprofloxacin. The unique ability of gyrase to introduce...
translation because the DNA cannot unwind properly. This group includes novobiocin, merbarone, and aclarubicin, which also have other significant mechanisms...
pseudintermedius. The S. saprophyticus and S. sciuri groups are generally novobiocin-resistant, as is S. hominis subsp. novobiosepticus. Members of the S....
to novobiocin, providing an important test to distinguish it from Staphylococcus saprophyticus, which is coagulase-negative, as well, but novobiocin-resistant...
equorum sp. nov. and S. kloosii sp. nov.: Three New Coagulase-Negative, Novobiocin-Resistant Species from Animals". Systematic and Applied Microbiology....
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
completely sequenced in 2002. The aminocoumarin antibiotics include: Novobiocin, Albamycin (Pharmacia And Upjohn) Coumermycin Clorobiocin The core of...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
penicillin, teicoplanin, erythromycin and tetracycline, and resistant to novobiocin. It is highly active biochemically, producing acid from a wide variety...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
Piqué N (August 2022). "Improvement of Mueller-Kauffman Tetrathionate-Novobiocin (MKTTn) enrichment medium for the detection of Salmonella enterica by...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
group. Poisons of type II topoisomerases include doxorubicin, etoposide, novobiocin, quinolones (including ciprofloxacin), and teniposide. These small molecules...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...
factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test Automated and point-of-care...