Chest pain or chest discomfort at rest or minimal exertion, or a new onset chest pain or discomfort on exertion.
Complications
Coronary artery disease
Unstable angina is a type of angina pectoris[1] that is irregular or more easily provoked.[2] It is classified as a type of acute coronary syndrome.[3]
It can be difficult to distinguish unstable angina from non-ST elevation (non-Q wave) myocardial infarction.[4][5] They differ primarily in whether the ischemia is severe enough to cause sufficient damage to the heart's muscular cells to release detectable quantities of a marker of injury, typically troponin T or troponin I.[4][6] Unstable angina is considered to be present in patients with ischemic symptoms suggestive of an acute coronary syndrome and no change in troponin levels, with or without changes indicative of ischemia (e.g., ST segment depression or transient elevation or new T wave inversion) on electrocardiograms.[4]
^Yeghiazarians Y, Braunstein JB, Askari A, Stone PH (January 2000). "Unstable angina pectoris". N. Engl. J. Med. 342 (2): 101–14. doi:10.1056/NEJM200001133420207. PMID 10631280.
^"unstable angina" at Dorland's Medical Dictionary
^Wiviott, S. D.; Braunwald, E (2004). "Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction: Part I. Initial Evaluation and Management, and Hospital Care". American Family Physician. 70 (3): 525–32. PMID 15317439.
^ abcCollet, Jean-Philippe; Thiele, Holger; Barbato, Emanuele; Barthélémy, Olivier; Bauersachs, Johann; et al. (2021-04-07). "2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation". European Heart Journal. 42 (14): 1289–1367. doi:10.1093/eurheartj/ehaa575. ISSN 1522-9645. PMID 32860058. Unstable angina is defined as myocardial ischaemia at rest or on minimal exertion in the absence of acute cardiomyocyte injury/necrosis. [...] Compared with NSTEMI patients, individuals with unstable angina do not experience acute cardiomyocyte injury/necrosis.
^Gulati, Martha; Levy, Phillip D.; Mukherjee, Debabrata; Amsterdam, Ezra; Bhatt, Deepak L.; et al. (2021-11-30). "2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines". Circulation. 144 (22): e368–e454. doi:10.1161/CIR.0000000000001029. ISSN 0009-7322. PMID 34709879.
^Barthélémy, Olivier; Jobs, Alexander; Meliga, Emanuele; et al. (2021-04-07). "Questions and answers on workup diagnosis and risk stratification: a companion document of the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation". European Heart Journal. 42 (14): 1379–1386. doi:10.1093/eurheartj/ehaa602. ISSN 1522-9645. PMC 8026278. PMID 32860030. NSTEMI is characterized by ischaemic symptoms associated with acute cardiomyocyte injury (=rise and/or fall in cardiac troponin T/I), while ischaemic symptoms at rest (or minimal effort) in the absence of acute cardiomyocyte injury define unstable angina. This translates into an increased risk of death in NSTEMI patients, while unstable angina patients are at relatively low short-term risk of death.
Unstableangina is a type of angina pectoris that is irregular or more easily provoked. It is classified as a type of acute coronary syndrome. It can...
angina can be quite severe. Worsening angina attacks, sudden-onset angina at rest, and angina lasting more than 15 minutes are symptoms of unstable angina...
Variant angina, also known as Prinzmetal angina, vasospastic angina, angina inversa, coronary vessel spasm, or coronary artery vasospasm, is a syndrome...
most common of the cardiovascular diseases. Types include stable angina, unstableangina, and myocardial infarction. A common symptom is chest pain or discomfort...
infarction (STEMI), non-ST elevation myocardial infarction (NSTEMI), or unstableangina. STEMI is characterised by complete blockage of a coronary artery resulting...
hospital ward specialized in the care of patients with heart attacks, unstableangina, cardiac dysrhythmia and (in practice) various other cardiac conditions...
whether or not the person is stable or unstable, and whether the instability is due to the tachycardia. Unstable means that either important organ functions...
United States, with more than 500 thousand prescriptions. Treatment of unstableangina (UA) and non-ST elevated myocardial infarction (NSTEMI), administered...
flow to the heart. Unlike the other type of acute coronary syndrome, unstableangina, a myocardial infarction occurs when there is cell death, which can...
segment depression and T-wave changes may be seen in patients with unstableangina Depressed but upsloping ST segment generally rules out ischemia as...
occlusion can lead to stable or unstableangina, myocardial infarction, and sudden cardiac death. Unlike classical angina pectoris, traditional cardiovascular...
2007). "ACC/AHA 2007 guidelines for the management of patients with unstableangina/non-ST-Elevation myocardial infarction: a report of the American College...
stable and unstable ischemic heart disease. Most commonly, aspirin is used as a single medication in cases of uncomplicated stable angina, and in some...
diabetes, uncontrolled hypertension, obesity, chronic kidney disease, and unstableangina. Left heart catheterization (LHC) is an ambiguous term and sometime...
(2007). "ACC/AHA 2007 Guidelines for the Management of Patients with UnstableAngina/Non-ST-Elevation Myocardial Infarction: Executive Summary: A Report...
especially under increased stress. Stable angina is chest pain on exertion that improves with rest. Unstableangina is chest pain that can occur at rest,...
still cause collapse in cases of severe stenosis. In unstableangina (excluding variant angina), amlodipine can cause a reflex increase in cardiac contractility...
infarction. ST elevation only occurs in full thickness infarction Prinzmetal's angina Acute pericarditis ST elevation in all leads (diffuse ST elevation) is more...
which assesses the risk of death and ischemic events in patients with unstableangina (UA) or non-ST elevation myocardial infarction (NSTEMI). In patients...
(myocardium). They are measured in the blood to differentiate between unstableangina and myocardial infarction (heart attack) in people with chest pain...
non-ST elevation acute coronary syndrome (NST-ACS); the latter includes unstableangina and non-ST elevation myocardial infarction (NSTEMI). Treatment is generally...
include: acute myocardial infarction (AMI) with early reperfusion unstableangina after percutaneous transluminal coronary angioplasty (PTCA) after cardiac...
rate, and contractility. Variant angina – it is effective owing to its direct effects on coronary dilation. Unstableangina (preinfarction, crescendo) – diltiazem...
history of a myocardial infarction, congestive heart failure, or recent angina, the wide complex tachycardia is much more likely to be ventricular tachycardia...
asymptomatic until it causes significant obstruction, leading to various forms of angina or eventually a myocardial infarction. Common warning symptoms are crushing...
using bacterial synthesized human Apo-A1 Milano HDL in people with unstableangina produced a fairly dramatic reduction in measured coronary plaque volume...
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